Li Cheng-tao
Institute of Forensic Sciences, Ministry of Justice, PR China, Shanghai 200063, China.
Fa Yi Xue Za Zhi. 2004;20(2):120-3.
Over a long period of time, studies on HLA structure and function have been the research hotspots. for it is very important to understand the essential of life science and disease mechanism. With the rapid development of molecular biology, HLA typing makes great progress. It has changed from traditional serological typing to DNA-based typing. More and more HLA genotyping methods have been developed and applied. In this essay, the author reviewed and appraised all kinds of HLA genotyping techniques and introduced two new techniques.
长期以来，对HLA结构与功能的研究一直是热点。因为这对于理解生命科学的本质和疾病机制非常重要。随着分子生物学的快速发展，HLA分型取得了巨大进展。它已从传统的血清学分型转变为基于DNA的分型。越来越多的HLA基因分型方法被开发和应用。在本文中，作者对各种HLA基因分型技术进行了综述和评价，并介绍了两种新技术。
