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[头颈部原发性结外非霍奇金恶性淋巴瘤的组织学与临床评估]

[Histologic and clinical assessment of primary extranodal non-Hodgkin malignant lymphomas of the head and neck region].

作者信息

Markowski Jarosław, Kajor Maciej, Gierek Tatiana, Witkowska Małgorzata, Kulesa Lukasz, Ligienza Maciej, Pajak Jacek, Wolańska-Karut Joanna

机构信息

Klinika Laryngologii Sl. AM w Katowicach.

出版信息

Otolaryngol Pol. 2004;58(3):429-35.

PMID:15311583
Abstract

The authors presented 27 cases of primary extranodal non-Hodgkin's malignant lymphomas of the head and neck area in patients treated surgically in the ENT Department in the years 1996-2001. We observed tumors in the various areas: palatine tonsil, naso-pharynx, eye socket, paranasal sinuses, parapharyngeal space and lingual base. In the course of the diagnostic process we examined the patients carefully to be sure that the cancer had not disseminated. We used some imaging techniques such as: ultrasonography, CT and MRI. We also used the needle aspiration biopsy, as a additional examination. However the material was not significant in the most cases and we were unable to make a definitive diagnosis on the basis of this method alone. After prior examinations we performed the radical operations and removed the tumours. In each case the postoperative material was examined using immunohistochemical methods. Afterwards the pathomorphological diagnosis was made by the specialists. Next the patients were observed and treated in the Haematological Department and Radiotherapy Department. In all cases pathomorphological diagnosis were performed on the base of usage postoperative histochemical examinations. All treated patients were performed as diagnostic preoperative USG, CT, MRI and fine-needle biopsy aspiration exam. All patients for further treatment were observed at Haematological Department.

摘要

作者报告了1996年至2001年间在耳鼻喉科接受手术治疗的27例头颈部原发性结外非霍奇金恶性淋巴瘤患者。我们观察到肿瘤发生在不同部位:腭扁桃体、鼻咽、眼眶、鼻窦、咽旁间隙和舌根。在诊断过程中,我们仔细检查患者以确保癌症未扩散。我们使用了一些成像技术,如超声检查、CT和MRI。我们还采用针吸活检作为辅助检查。然而,在大多数情况下,该材料意义不大,我们无法仅基于此方法做出明确诊断。在进行前期检查后,我们实施了根治性手术并切除肿瘤。在每例病例中,术后材料均采用免疫组织化学方法进行检查。之后由专家做出病理形态学诊断。接下来,患者在血液科和放疗科接受观察和治疗。在所有病例中,病理形态学诊断均基于术后组织化学检查。所有接受治疗的患者均进行了术前诊断性超声检查、CT、MRI和细针穿刺活检抽吸检查。所有需要进一步治疗的患者均在血液科接受观察。

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