de Boer Michiel R, Pluijm Saskia M F, Lips Paul, Moll Annette C, Völker-Dieben Hennie J, Deeg Dorly J H, van Rens Ger H M B
Department of Ophthalmology, VU University Medical Center, Amsterdam 1007 MB, The Netherlands.
J Bone Miner Res. 2004 Sep;19(9):1539-47. doi: 10.1359/JBMR.040504. Epub 2004 May 10.
Visual impairment has been implicated as a risk factor for falling and fractures, but results of previous studies have been inconsistent. The relationship between several aspects of vision and falling/fractures were examined in a prospective cohort study in 1,509 older men and women. The analyses showed that impaired vision is an independent risk factor for both recurrent falling and fractures.
Falls and fractures are a major health problem among the elderly. Visual impairment has been implicated as a risk factor for both falls and fractures. However, results from studies are inconsistent. The inconsistency between findings can primarily be attributed to differences in the designs of these studies. Most studies have been cross-sectional or case-control studies, and many have not correctly adjusted for potential confounders. Furthermore, until now, the potential mediating effects of functional limitation, physical performance, and physical activity have not been examined.
A total of 1,509 people was examined in 1995-1996. Contrast sensitivity was assessed with the VCTS_6000-1 chart for near vision. In addition, self-reported visual impairment was assessed by questions on recognizing faces from a distance of 4 m, reading the small print in the newspaper, and problems with glare. Furthermore, many potential confounders and mediators were assessed. Falls and fractures were assessed prospectively during a 3-year follow-up period. The associations between the vision variables and falls and fractures were examined using Cox proportional hazards analyses.
After adjustment for potential confounders, contrast sensitivity was shown to be associated with recurrent falling (hazard ratio [HR] = 1.5), and the question on recognizing faces was shown to be associated with fractures (HR = 3.1). Furthermore, functional limitations and physical performance were shown to be mediators in the relationship between vision variables and recurrent falling/fractures.
The results indicate that impaired vision is an independent risk factor for falling and fractures, but different aspects of visual functioning may have different relationships to falling and fractures.
视力障碍被认为是跌倒和骨折的一个风险因素,但以往研究结果并不一致。在一项针对1509名老年男性和女性的前瞻性队列研究中,对视力的几个方面与跌倒/骨折之间的关系进行了研究。分析表明,视力受损是反复跌倒和骨折的独立风险因素。
跌倒和骨折是老年人的一个主要健康问题。视力障碍被认为是跌倒和骨折的一个风险因素。然而,研究结果并不一致。研究结果之间的不一致主要可归因于这些研究设计的差异。大多数研究是横断面研究或病例对照研究,许多研究没有正确调整潜在的混杂因素。此外,到目前为止,功能受限、身体机能和身体活动的潜在中介作用尚未得到研究。
1995年至1996年共对1509人进行了检查。使用VCTS_6000 - 1图表评估近视力的对比敏感度。此外,通过关于在4米远处识别面部、阅读报纸上的小字以及眩光问题的提问来评估自我报告的视力障碍。此外,还评估了许多潜在的混杂因素和中介因素。在3年的随访期内对跌倒和骨折进行前瞻性评估。使用Cox比例风险分析来研究视力变量与跌倒和骨折之间的关联。
在调整潜在混杂因素后,对比敏感度与反复跌倒相关(风险比[HR] = 1.5),识别面部的问题与骨折相关(HR = 3.1)。此外,功能受限和身体机能被证明是视力变量与反复跌倒/骨折之间关系的中介因素。
结果表明,视力受损是跌倒和骨折的独立风险因素,但视觉功能的不同方面与跌倒和骨折可能有不同的关系。