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[急性缺血性卒中的TOAST分型]

[TOAST subtyping of acute ischemic stroke].

作者信息

Zhou Heng, Wang Yong-jun, Wang Su-xiang, Zhao Xing-quan

机构信息

Department of Neurology, Beijing Tiantan Hospital Capital University of Medical Sciences, Beijing 100050, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2004 Jul;43(7):495-8.

PMID:15312401
Abstract

OBJECTIVE

To determine the etiological characteristics of ischemic stroke in Chinese people on the basis of Trial of Org 10 172 in Acute Stroke Treatment (TOAST) criteria.

METHODS

300 patients with ischemic stroke were recruited into this study. Ischemic stroke was classified into five subtypes based on clinical manifestations, MRI, MRA and DSA.

RESULTS

Of all the ischemic stroke patients, 12.3%, 40.0%, 31.3%, 5.0%, and 11.4% were classified as cardio embolism, large-artery atherosclerotic, lacunare, of other demonstrated etiology and of undetermined etiology.

CONCLUSIONS

The statistical comparison between male and female of each subtype is not significant. The relative incidence of large-artery atherosclerosis in Chinese patients is higher than that of all the other four subtypes.

摘要

目的

基于急性卒中治疗中奥扎格雷10172试验(TOAST)标准,确定中国人群缺血性卒中的病因学特征。

方法

300例缺血性卒中患者纳入本研究。根据临床表现、MRI、MRA和DSA将缺血性卒中分为五个亚型。

结果

在所有缺血性卒中患者中,12.3%、40.0%、31.3%、5.0%和11.4%被分类为心源性栓塞、大动脉粥样硬化、腔隙性、其他明确病因和病因不明。

结论

各亚型的男性和女性之间的统计学比较无显著性差异。中国患者中大动脉粥样硬化的相对发病率高于其他四种亚型。

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引用本文的文献

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Recurrence Rate and Relevant Associated Factors of Stroke among Patients with Small Artery Occlusion in Northern China.中国北方小动脉闭塞患者卒中的复发率及相关影响因素。
Sci Rep. 2019 Feb 26;9(1):2834. doi: 10.1038/s41598-019-39207-0.
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Association between Elevated Hemoglobin A1c Levels and the Outcomes of Patients with Small-Artery Occlusion: A Hospital-Based Study.糖化血红蛋白水平升高与小动脉闭塞患者预后的关系:一项基于医院的研究。
PLoS One. 2016 Aug 3;11(8):e0160223. doi: 10.1371/journal.pone.0160223. eCollection 2016.
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Comparison of Risk Factor between Lacunar Stroke and Large Artery Atherosclerosis Stroke: A Cross-Sectional Study in China.
腔隙性卒中与大动脉粥样硬化性卒中危险因素的比较:一项中国的横断面研究
PLoS One. 2016 Mar 2;11(3):e0149605. doi: 10.1371/journal.pone.0149605. eCollection 2016.
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The relationship between plasma D-dimer levels and outcome of Chinese acute ischemic stroke patients in different stroke subtypes.血浆 D-二聚体水平与不同脑卒中亚型的中国急性缺血性脑卒中患者结局的关系。
J Neural Transm (Vienna). 2014 Apr;121(4):409-13. doi: 10.1007/s00702-013-1113-y. Epub 2013 Nov 8.