Lelik M P, Efanov E A
Anesteziol Reanimatol. 2004 May-Jun(3):41-3.
Nosocomial infections in perinatology are the leading factor affecting both the clinical course and outcome of the main disease in newborns with the artificial lung ventilation management (ALV). We undertook controllable randomized examinations of 161 newborns with ALV receiving different immunotherapy schemes for the purpose of assessing the effects of different immunotherapy methods inducing the onset and progression of the above complications. We also analyzed the clinical-and-immunologic efficiency of the suggested immunotherapy schemes in respect to a variety of the most important indices; it showed an obvious advantage of the intravenous immunoglobulin administration in doses exceeding the routine ones as well as of using the plasma cryoprecipitate for the purpose of preventing the in-hospital infections in newborns.
围产医学中的医院感染是影响接受人工肺通气管理(ALV)的新生儿主要疾病临床病程和结局的主要因素。我们对161例接受不同免疫治疗方案的ALV新生儿进行了可控随机检查,目的是评估不同免疫治疗方法对上述并发症发生和发展的影响。我们还针对各种最重要指标分析了所建议免疫治疗方案的临床和免疫效果;结果显示,静脉注射超过常规剂量的免疫球蛋白以及使用血浆冷沉淀预防新生儿医院感染具有明显优势。