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CT检查在评估食管癌新辅助化疗疗效中的作用

Role of CT examination in assessing the response of oesophageal carcinoma to neoadjuvant chemotherapy.

作者信息

Krupski Witold, Pasławski Marek, Złomaniec Janusz, Ciechański Aleksander, Dabrowski Andrzej

机构信息

2nd Department of Radiology, Medical University of Lublin.

出版信息

Ann Univ Mariae Curie Sklodowska Med. 2003;58(1):333-7.

PMID:15315010
Abstract

The oesophageal carcinoma is a devastating disease with very poor prognosis. In many cases surgery with previous radiation or chemotherapy are used in treatment. The assessment of the oesophageal tumour response to chemotherapy is very important, because early detection of tumour response to antineoplastic therapy may improve the value of such an approach by allowing continuation of treatment in those likely to benefit while preventing the administration of ineffective and potentially harmful therapy in non-responders. The CT evaluation is a reliable method of monitoring patients during chemotherapy due to oesophageal carcinoma. It can detect reduction of the infiltration thickness, size of enlarged lymph nodes as well as reduction of the angle of aortic infiltration. Unlike in oesophageal ultrasonography, even highly stenotic tumours can be fully assessed in CT.

摘要

食管癌是一种预后极差的毁灭性疾病。在许多情况下,治疗采用手术联合先前的放疗或化疗。评估食管肿瘤对化疗的反应非常重要,因为早期检测肿瘤对抗肿瘤治疗的反应可能会提高这种治疗方法的价值,即允许对可能受益的患者继续进行治疗,同时防止对无反应者给予无效且可能有害的治疗。CT评估是监测食管癌患者化疗期间的可靠方法。它可以检测浸润厚度的减小、肿大淋巴结的大小以及主动脉浸润角度的减小。与食管超声检查不同,即使是高度狭窄的肿瘤在CT中也能得到全面评估。

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