[卡尔塔吉罗内（西西里岛）地区产超广谱β-内酰胺酶（ESBL）肠杆菌科细菌的发病率]
[Incidence of extended spectrum beta-lactamase (ESBL)-producing Enterobacteria in the area of Caltagirone (Sicily)].
作者信息
Bellissima Pietro, Amato Rosalba
机构信息
U.O.C. di Malattie Infettive, Azienda Ospedaliera Gravina, Caltagirone (CT), Italy.
出版信息
Infez Med. 2004 Jun;12(2):108-12.
The authors report the incidence of extended spectrum b-lactamases (ESBL)- producing strains in 1,602 enterobacteria consecutively isolated, from April 2002 to December 2003, in Caltagirone (CT) Hospital, and their in vitro susceptibility to several antimicrobial agents. The incidence of ESBL-producing Enterobacteria was equal to 1.5%, mainly among Escherichia coli, Klebsiella spp and Citrobacter koseri, isolated by emergency and medicine wards. In vitro, the enterobacteria were fully susceptible to carbapenems and highly susceptible to third-generation cephalosporin, aztreonam, piperacillin, amikacin, and ciprofloxacin.
作者报告了2002年4月至2003年12月期间在卡尔塔吉罗内（CT）医院连续分离出的1602株肠杆菌科细菌中产超广谱β-内酰胺酶（ESBL）菌株的发生率，以及它们对几种抗菌药物的体外敏感性。产ESBL肠杆菌科细菌的发生率为1.5%，主要见于大肠杆菌、克雷伯菌属和科氏柠檬酸杆菌，由急诊科和内科病房分离得到。体外试验中，肠杆菌科细菌对碳青霉烯类药物完全敏感，对第三代头孢菌素、氨曲南、哌拉西林、阿米卡星和环丙沙星高度敏感。
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