Mendenhall William M, Amos E Henry, Rout W Robert, Zlotecki Robert A, Hochwald Steven N, Cance William G
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville 32610, USA.
Cancer. 2004 Sep 15;101(6):1338-44. doi: 10.1002/cncr.20526.
The objective of this report was to review the role of adjuvant postoperative radiotherapy (RT) for patients with adenocarcinoma of the colon.
The authors reviewed the pertinent literature.
Data suggested that locoregional postoperative RT improves both local control and survival for patients with T4N0-N1 tumors. There also may be a benefit for patients with T3N1-N2 tumors, but the data were equivocal. Whole abdominal RT may result in a similar benefit but is associated with increased toxicity.
Postoperative RT should be considered for patients with T4N0-N1 colon carcinoma. Locoregional fields should be used.
本报告的目的是回顾辅助性术后放疗（RT）在结肠癌患者中的作用。
作者回顾了相关文献。
数据表明，局部区域术后放疗可改善T4N0 - N1期肿瘤患者的局部控制率和生存率。对于T3N1 - N2期肿瘤患者可能也有益处，但数据并不明确。全腹放疗可能会带来类似的益处，但会增加毒性。
T4N0 - N1期结肠癌患者应考虑术后放疗。应采用局部区域照射野。
