Luo Zhong-Cheng, Kierans William J, Wilkins Russell, Liston Robert M, Uh Soo-Hong, Kramer Michael S
Department of Epidemiology and Biostatistics, McGill University, Canada.
Int J Epidemiol. 2004 Dec;33(6):1252-9. doi: 10.1093/ije/dyh290. Epub 2004 Aug 19.
Increasingly more First Nations (FN) people have moved from rural to urban areas. It is unknown how disparities in infant mortality among FN versus non-FN women have changed over time in urban versus rural areas.
We conducted a birth cohort-based study of all 877 925 live births (56 771 FN and 821 154 non-FN) registered in British Columbia, 1981-2000. Main outcomes included rates, risk differences, and relative risks of neonatal, postneonatal, and overall infant death.
Both neonatal and postneonatal mortality rates for FN infants showed a steady decline in rural areas but a rise-and-fall pattern in urban areas. Relative risks for overall infant death among FN versus non-FN infants declined steadily from 2.75 (95% CI: 2.04, 3.72) to 1.87 (95% CI: 1.24, 2.81) in rural areas from 1981-1984 to 1997-2000, but rose from 1.59 (95% CI: 1.27, 1.99) (1981-1984) to 2.80 (2.33-3.37) (1989-92) and then fell to 1.89 (1.44-2.49) (1997-2000) in urban areas. Risk differences for neonatal death among FN versus non-FN infants declined substantially over time in rural but not urban areas. The disparities in neonatal death among FN versus non-FN were largely explained by differences in preterm birth, while the disparities in postneonatal death were not explained by observed maternal and pregnancy characteristics.
Reductions in disparities in infant mortality among FN versus non-FN women have been less substantial and consistent over time in urban versus rural areas of British Columbia, suggesting the need for greater attention to FN maternal and infant health in urban areas.
越来越多的原住民(FN)人口从农村地区迁移到了城市地区。目前尚不清楚原住民与非原住民女性之间的婴儿死亡率差异在城市和农村地区随时间发生了怎样的变化。
我们对1981年至2000年在不列颠哥伦比亚省登记的所有877925例活产(56771例原住民和821154例非原住民)进行了一项基于出生队列的研究。主要结局包括新生儿、新生儿后期和总体婴儿死亡的发生率、风险差异和相对风险。
原住民婴儿的新生儿和新生儿后期死亡率在农村地区呈稳步下降趋势,但在城市地区呈先上升后下降的模式。1981 - 1984年至1997 - 2000年期间,农村地区原住民与非原住民婴儿总体死亡的相对风险从2.75(95%置信区间:2.04,3.72)稳步下降至1.87(95%置信区间:1.24,2.81),而在城市地区,该相对风险从1.59(95%置信区间:1.27,1.99)(1981 - 1984年)升至2.80(2.33 - 3.37)(1989 - 1992年),随后又降至1.89(1.44 - 2.49)(1997 - 2000年)。农村地区原住民与非原住民婴儿的新生儿死亡风险差异随时间大幅下降,而城市地区则未下降。原住民与非原住民之间新生儿死亡的差异在很大程度上可由早产差异解释,而新生儿后期死亡的差异无法由观察到的母亲和妊娠特征解释。
在不列颠哥伦比亚省的城市和农村地区,随着时间推移,原住民与非原住民女性之间婴儿死亡率差异的缩小幅度较小且不一致,这表明需要更加关注城市地区原住民的母婴健康。