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心脏手术后房颤相关的危险因素、发病率和死亡率。

Risk factors, morbidity, and mortality associated with atrial fibrillation in the postoperative period of cardiac surgery.

作者信息

Silva Rogério Gomes da, Lima Gustavo Glotz de, Laranjeira Andréia, Costa Altamiro Reis da, Pereira Edemar, Rodrigues Rubem

机构信息

Instituto de Cardiologia do Rio Grande do Sul, Fundação Univeresitária de Cardiologia, Porto Alegre, RS, Brazil.

出版信息

Arq Bras Cardiol. 2004 Aug;83(2):105-10; 99-104. Epub 2004 Aug 17.

Abstract

OBJECTIVE

To determine the incidence of atrial fibrillation in the postoperative period of cardiac surgery, its impact on morbidity, mortality, and hospital stay, and to analyze the risk factors in the pre, trans, and postoperative periods.

METHOD

Contemporary cohort study with 158 adult patients undergoing cardiac surgery, of whom those with atrial fibrillation in the preoperative period were excluded. The patients were assessed with continuous cardiac monitoring and daily electrocardiograms. Any episode of irregular rhythm with the presence of f waves of variable morphology and amplitude was considered atrial fibrillation.

RESULTS

The general incidence of atrial fibrillation was 28.5%, being 21.6% for revascularized patients and 44.3% for those undergoing valvular repair. Factors independently associated with atrial fibrillation were left heart failure in the preoperative period (p=0.05; RC=2.2), total fluid balance (p=0.01; RC=1.0), duration of surgery (p=0.03; RC=1.01) [and other associated factors, age > 70 years, aortic valvular disease, psychomotor agitation, length of installation of the drains, pulmonary congestion and respiratory insufficiency in the postoperative period]. The use of beta-blockers (p=0.01; RC=0.3) was a protective factor. Atrial fibrillation in the postoperative period was associated with an increase in the length of hospital stay (16.9+/-12.3 days versus 9.2+/-4.0 days, p<0.001) and a greater incidence of stroke or postoperative death (p=0.02).

CONCLUSION

The incidence of atrial fibrillation in the postoperative period of cardiac surgery was high and caused a significant increase in morbidity, mortality, and the length of hospital stay. Among the independent risk factors, excessive fluid balance is significant. The use of beta-blockers was identified as a protective factor.

摘要

目的

确定心脏手术后房颤的发生率、其对发病率、死亡率及住院时间的影响,并分析术前、术中及术后阶段的危险因素。

方法

对158例接受心脏手术的成年患者进行当代队列研究,排除术前有房颤的患者。对患者进行连续心脏监测及每日心电图检查。任何伴有形态和振幅可变的f波的心律不齐发作均被视为房颤。

结果

房颤的总体发生率为28.5%,血管重建患者为21.6%,瓣膜修复患者为44.3%。与房颤独立相关的因素有术前左心衰竭(p=0.05;相对危险度=2.2)、总液体平衡(p=0.01;相对危险度=1.0)、手术时间(p=0.03;相对危险度=1.01)[以及其他相关因素,年龄>70岁、主动脉瓣膜疾病、精神运动性激越、引流管放置时间、术后肺淤血及呼吸功能不全]。使用β受体阻滞剂(p=0.01;相对危险度=0.3)是一个保护因素。术后房颤与住院时间延长(16.9±12.3天对9.2±4.0天,p<0.001)及中风或术后死亡发生率增加相关(p=0.02)。

结论

心脏手术后房颤的发生率较高,导致发病率、死亡率及住院时间显著增加。在独立危险因素中,液体平衡过多具有重要意义。β受体阻滞剂的使用被确定为一个保护因素。

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