Fröbe Martin, Kullmann Frank, Schölmerich Jürgen, Böhme Thorsten, Müller-Ladner Ulf
Medizinische Klinik II, Klinikum St. Marien Amberg, Amberg.
Med Klin (Munich). 2004 Jul 15;99(7):391-5. doi: 10.1007/s00063-004-1057-4.
A 43-year-old, cachectic, alcohol-addicted patient was admitted to the hospital due to hemoptysis and fever of up to 40 degrees C for the last 4 days. Physical examination revealed pleural rubs in the right lower lung and a diffuse pain in the right upper quadrant of the abdomen. The right upper quadrant of the abdomen also showed scars from several surgical interventions on the small intestine, the liver and the biliary tract and deformed caudal ribs due to an accident 23 years earlier.
DIAGNOSTICS, THERAPY, AND CLINICAL COURSE: Chest X-ray, ultrasound and computed tomography (CT) showed abscess cavities in lung and liver communicating through the diaphragm. Under antibiotic therapy the abscess was drained. Cultures showed Klebsiella pneumoniae and Streptococcus viridans. Continuous lavage of the abscess cavities and antibiotic therapy led to an improvement in parameters of inflammation and clinical status. Imaging after 10 days of treatment showed a contrast enrichment in the abscess cavities and a bronchobiliary fistula accounting for temporary biliptysis. The drainage was removed after 29 days, when similar imaging revealed no further sign of an abscess cavity and a previous CT follow-up had proven a distinct decrease of the abscesses.
Bronchobiliary fistulas are very rare. In most cases they are caused by hepatic or subphrenic abscesses, resulting from different conditions. The development of an bronchobiliary fistula originating from a Klebsiella pneumoniae pneumonia, as indicated by this report, has not been described so far. In the patient presented here, treatment was achieved due to continuous drainage despite the large extent of the abscess.
一名43岁、消瘦且酗酒成瘾的患者因咯血和持续4天高达40摄氏度的发热入院。体格检查发现右下肺有胸膜摩擦音,右上腹弥漫性疼痛。右上腹还可见小肠、肝脏和胆道多次手术留下的疤痕,以及23年前因意外导致的尾肋畸形。
诊断、治疗与临床病程:胸部X光、超声和计算机断层扫描(CT)显示肺和肝内的脓肿腔通过膈肌相通。在抗生素治疗下,脓肿得以引流。培养结果显示为肺炎克雷伯菌和草绿色链球菌。对脓肿腔持续冲洗并进行抗生素治疗后,炎症指标和临床状况有所改善。治疗10天后的影像学检查显示脓肿腔内有造影剂充盈,且存在支气管胆管瘘,这是导致暂时性胆咯血的原因。29天后引流管拔除,此时类似的影像学检查显示脓肿腔无进一步迹象,之前的CT随访已证实脓肿明显缩小。
支气管胆管瘘非常罕见。在大多数情况下,它们由不同病因引起的肝脓肿或膈下脓肿导致。本报告所示的由肺炎克雷伯菌肺炎引发支气管胆管瘘的情况,此前尚未见报道。在此例患者中,尽管脓肿范围较大,但通过持续引流实现了治疗。