[Interrelationship between contact coagulation, surface charge and roughness].

The negative surface charge and the mechanically even surface were found in vitro to hinder the blood hypercoagulation, fibrin absorption, and thrombocytes hyperadhesion. The surface negative electrical charge of 6--10(-9)Cl/cm2 and the surface of the 9--14th class of mechanical evenness seem to be optimal for prophylaxis of thrombosis at the blood-surface border. The surface negative electrical charge reduces the possibility of thrombosis on mechanically rough surface.