[18F]氟脱氧葡萄糖正电子发射断层扫描在癫痫评估中的作用。

The role of positron emission tomography with [18F]fluorodeoxyglucose in the evaluation of the epilepsies.

作者信息

Henry Thomas R, Votaw John R

机构信息

Department of Neurology, Emory University School of Medicine, Woodruff Memorial Building, Suite 6000, PO Drawer V, 1639 Pierce Drive, Atlanta, GA 30322, USA.

出版信息

Neuroimaging Clin N Am. 2004 Aug;14(3):517-35, ix. doi: 10.1016/j.nic.2004.04.011.

DOI:10.1016/j.nic.2004.04.011

PMID:15324862

Abstract

Cerebral glucose metabolic mapping using positron emission tomography (PET) and 2-[18F]fluoro-2-deoxyglucose (FDG) has been extensively studied in the epilepsies. Regions of interictal glucose hypometabolism are highly associated with cerebral sites of seizure generation-propagation in focal epilepsies. The volume of reduced glucose metabolism is often widespread and even bilateral in focal epilepsies, although ictal onset zones typically are located at the sites of most severe hypometabolism within a larger volume of hypometabolism.

摘要

使用正电子发射断层扫描（PET）和2-[18F]氟-2-脱氧葡萄糖（FDG）进行的脑葡萄糖代谢图谱在癫痫研究中已得到广泛应用。发作间期葡萄糖代谢减低区域与局灶性癫痫发作的起始-传播脑区高度相关。在局灶性癫痫中，葡萄糖代谢减低的区域通常广泛存在，甚至双侧受累，尽管发作起始区通常位于更大范围代谢减低区内代谢最严重的部位。