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2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands.

作者信息

Prisinzano Thomas, Dukat Małgorzata, Law Ho, Slassi Abdelmalik, MacLean Neil, DeLannoy Inés, Glennon Richard A

机构信息

Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.

出版信息

Bioorg Med Chem Lett. 2004 Sep 20;14(18):4697-9. doi: 10.1016/j.bmcl.2004.06.085.

DOI:10.1016/j.bmcl.2004.06.085
PMID:15324890
Abstract

2-(Anilino)imidazolines were identified as novel human 5-HT(1D) receptor ligands, but offered no particular advantage over previously reported 2-(benzyl)imidazolines. Pharmacokinetic and functional data were obtained for selected 2-(benzyl)imidazoline derivatives.

摘要

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