Armstrong Sarah R, Green Laura C
Cambridge Environmental Inc., 58 Charles Street, Cambridge, MA 02141, USA.
Clin Occup Environ Med. 2004 Aug;4(3):481-96, vi. doi: 10.1016/j.coem.2004.03.005.
Chlorinated hydrocarbon solvents, such as trichloroethylene and 1,1,1-trichloroethane, have been used widely in many industries because of their ready ability to dissolve oils, greases, and other materials, their low acute toxicity, and their non-flammability. Although these materials share certain toxicologic, functional, and chemical similarities, important differences exist. These differences largely explain why certain solvents, once common, are no longer in use and why others have become more widely used over time. This article reviews the properties, toxicologic effects of interest, workplace limits, and use history of the most common chlorinated hydrocarbon solvents.
氯代烃溶剂,如三氯乙烯和1,1,1 - 三氯乙烷,因其能够轻易溶解油类、油脂及其他物质、急性毒性低且不易燃,而在许多行业中得到广泛应用。尽管这些物质在毒理学、功能和化学性质上有一定相似性,但也存在重要差异。这些差异在很大程度上解释了为何某些曾经常用的溶剂已不再使用,以及为何其他溶剂随着时间推移使用得更为广泛。本文综述了最常见氯代烃溶剂的性质、相关毒理学效应、工作场所接触限值及使用历史。