依达拉奉对急性心肌梗死患者再灌注损伤的影响。
Effects of edaravone on reperfusion injury in patients with acute myocardial infarction.
作者信息
Tsujita Kenichi, Shimomura Hideki, Kawano Hiroaki, Hokamaki Jun, Fukuda Masaya, Yamashita Takuro, Hida Satoru, Nakamura Yoshinori, Nagayoshi Yasuhiro, Sakamoto Tomohiro, Yoshimura Michihiro, Arai Hidekazu, Ogawa Hisao
机构信息
Department of Cardiology, Fukuoka Tokushukai Medical Center, 4-5 Sugu-kita, Kasuga City, Fukuoka 816-0864, Japan.
出版信息
Am J Cardiol. 2004 Aug 15;94(4):481-4. doi: 10.1016/j.amjcard.2004.05.007.
This clinical pilot study was a randomized, controlled, open-label study in 80 patients with acute myocardial infarction and was designed to examine the effects of a novel free radical scavenger, edaravone. Administration of edaravone before myocardial reperfusion was associated with smaller enzymatic infarcts and better clinical outcome.
这项临床试点研究是一项针对80例急性心肌梗死患者的随机、对照、开放标签研究，旨在研究新型自由基清除剂依达拉奉的效果。在心肌再灌注前给予依达拉奉与酶促梗死面积较小和更好的临床结局相关。
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