Denis Olivier, Deplano Ariane, Nonhoff Claire, De Ryck Raf, de Mendonça Ricardo, Rottiers Sylvianne, Vanhoof Raymond, Struelens Marc J
Department of Microbiology, Hôpital Erasme, 808, route de Lennik, 1070 Brussels, Belgium.
Antimicrob Agents Chemother. 2004 Sep;48(9):3625-9. doi: 10.1128/AAC.48.9.3625-3629.2004.
Methicillin-resistant Staphylococcus aureus (MRSA) strains (n = 455) collected in 2001 from 100 Belgian hospitals were characterized by molecular typing and by resistance gene distribution to macrolides-lincosamides-streptogramins and to aminoglycoside antibiotics. Rapid diversification of MRSA clones, compared with results of previous surveys, was evidenced by the broad geographic distribution of seven major clones belonging to the pandemic MRSA clonal complexes 5, 8, 22, 30, and 45 by multilocus sequence typing.
2001年从100家比利时医院收集的455株耐甲氧西林金黄色葡萄球菌（MRSA）菌株，通过分子分型以及对大环内酯类-林可酰胺类-链阳菌素类和氨基糖苷类抗生素的耐药基因分布情况进行了特征分析。多位点序列分型显示，与之前的调查结果相比，耐甲氧西林金黄色葡萄球菌克隆出现了快速多样化，这表现为属于大流行耐甲氧西林金黄色葡萄球菌克隆复合体5、8、22、30和45的7个主要克隆具有广泛的地理分布。
