Suppr超能文献

通过自我管理问卷评估前列腺癌根治术后挽救性放射治疗后的尿失禁情况:一项前瞻性研究

Urinary continence after salvage radiation therapy following radical prostatectomy, assessed by a self-administered questionnaire: a prospective study.

作者信息

Fontaine Eric, Ben Mouelli Sami, Thomas Laurent, Otmezguine Yves, Beurton Daniel

机构信息

Department of Urology, Ambroise Pare Hospital, University of West Paris, France.

出版信息

BJU Int. 2004 Sep;94(4):521-3. doi: 10.1111/j.1464-410X.2004.04995.x.

Abstract

OBJECTIVE

To evaluate urinary continence after salvage radiotherapy following radical prostatectomy (RP) for clinically localized prostate cancer.

PATIENTS AND METHODS

In all, 145 men had a retropubic RP in our department between 1992 and 2000. From this group, salvage radiotherapy with the dose of 65 Gy was given to 18 patients for a rising prostatic specific antigen (PSA) level. The mean (range) age at RP was 63 (50-72) years and the initial PSA level 14.95 (4.8-34) ng/mL. The radiotherapy was given at 46 (6-96) months after RP. A self-administered questionnaire about their urinary status was mailed to the patients before and 18 months after radiotherapy. The mean follow-up after radiotherapy was 34 (20-70) months.

RESULTS

Before radiotherapy, 17 patients were continent (defining continence as no regular use of pads). After salvage radiotherapy, 16 men had had no change in their urinary status, even for the one patient using pads. One patient with stress urinary incontinence showed a slight worsening of his urinary status after radiotherapy. Another patient who was continent before radiotherapy developed urgency with no urinary leakage. Fourteen men stated that they were very satisfied or satisfied about their urinary status after radiotherapy and four were mildly satisfied. Nine would undergo radiotherapy again even with their present continence status and nine probably would.

CONCLUSION

Using an anonymous self-administered questionnaire, salvage radiotherapy for a rising PSA level seems to be safe and does not worsen the continence achieved after RP in most patients.

摘要

目的

评估临床局限性前列腺癌根治性前列腺切除术(RP)后挽救性放疗后的尿失禁情况。

患者与方法

1992年至2000年间,共有145名男性在我科接受了耻骨后RP手术。在该组患者中,18名患者因前列腺特异性抗原(PSA)水平升高接受了剂量为65 Gy的挽救性放疗。RP时的平均(范围)年龄为63(50 - 72)岁,初始PSA水平为14.95(4.8 - 34)ng/mL。放疗在RP后46(6 - 96)个月进行。在放疗前及放疗后18个月,向患者邮寄了一份关于其排尿状况的自我调查问卷。放疗后的平均随访时间为34(20 - 70)个月。

结果

放疗前,17名患者尿控良好(将尿控定义为不经常使用尿垫)。挽救性放疗后,16名男性的排尿状况没有变化,即使是对于使用尿垫的那名患者。1名压力性尿失禁患者放疗后排尿状况略有恶化。另1名放疗前尿控良好的患者出现尿急但无尿漏。14名男性表示对放疗后的排尿状况非常满意或满意,4名表示中度满意。9名患者即使以目前的尿控状况仍愿意再次接受放疗,9名可能愿意。

结论

使用匿名自我调查问卷,PSA水平升高时进行挽救性放疗似乎是安全的,且在大多数患者中不会使RP后已获得的尿控情况恶化。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验