Wang Zhen, Teng Yong, Li Di-Chen, Liu Fei, Guo Zheng, Sun Zheng, Guo Zheng, Sun Zheng, Wang Hai-Qiang, Huan Yi, Gong Xue-Peng
Department of Orthopaedics, Xijing Hospital, Forth Military Medical University, Xi'an 710032, China.
Zhonghua Wai Ke Za Zhi. 2004 Jun 22;42(12):746-9.
To design and manufacture a new custom-made artificial articular cartilage of femoral condyle based on rapid prototyping technique and explore a method to solve the necroses of allocartilage in hemi joint allotransplantation.
Design the new custom-made artificial articular cartilage of femoral condyle. The allograft and the patient distal femurs were scanned with Picker 6000 spiral computed tomography (CT) with 1.0 slice thickness and pitch of 1.5, reconstructed the distal femurs in Voxel Q image workstation with volume rendering technique. Then downloaded the transaxial 2D image data to personal computer at 0.1 mm interval and converted it into 2D digitized contour data by using image processing software developed by our team. The 3D wire frame and solid images of femoral condyle could be reconstructed when the 2D digitized contour data were input into image processing software Surfacer 9.0 (Imageware Company, USA). Subsequently based on the clinical experience and the need of design, the 3D contour image of articular cartilage was extracted from the surrounding. Based on the extracted 3D contour image, the computer-aided design (CAD) of the custom-made artificial articular cartilage was accomplished in Surfacer software, converted the CAD model into RP data format. Standard triangularization language, imported into the LPS600 rapid prototyping machine (Hengtong Company, Xi'an Jiaotong University, China), and the resin prototype was achieved. Then the resin model was used as a positive mould to build up a silica gel negative mould, the negative mould was sent to the factory to manufacture Ti-6Al-4V alloy articular cartilage through ordinary mould-melted founding process. Finally, the whole metal cartilage was completed after melting two special cages on it. A patient was selected to clinical applying.
A new custom-made artificial articular cartilage of femoral condyle was made. It was press-fit well to the subchondral bone of the allograft bone. The patient's one and half year follow-up result was excellent.
We design and manufacture a new custom-made artificial articular cartilage of femoral condyle based on rapid prototyping technique. The result shows that the manufacturing process has the advantage of rapidness and precision that are very important for individualized artificial implant manufacturing. The artificial articular cartilage is press-fit well and could be a good idea to solve the necroses of allocartilage in hemijoint allotransplantation.
基于快速成型技术设计制造新型定制化股骨髁人工关节软骨，探索解决半关节同种异体移植中异体软骨坏死的方法。
设计新型定制化股骨髁人工关节软骨。采用Picker 6000螺旋CT对同种异体骨和患者股骨远端进行扫描，层厚1.0mm，螺距1.5，在Voxel Q图像工作站用容积再现技术重建股骨远端。然后以0.1mm间隔将横断面二维图像数据下载到个人计算机，并用本团队开发的图像处理软件将其转换为二维数字化轮廓数据。将二维数字化轮廓数据输入图像处理软件Surfacer 9.0（美国Imageware公司），可重建股骨髁的三维线框和实体图像。随后根据临床经验和设计需要，从周围提取关节软骨的三维轮廓图像。基于提取的三维轮廓图像，在Surfacer软件中完成定制化人工关节软骨的计算机辅助设计（CAD），将CAD模型转换为RP数据格式。用标准三角化语言，导入LPS600快速成型机（中国西安交通大学恒通公司），制成树脂原型。然后以树脂模型为阳模制作硅胶阴模，将阴模送工厂通过普通模熔铸工艺制造Ti-6Al-4V合金关节软骨。最后在其上熔接两个特制的骨笼后完成整个金属软骨。选取1例患者进行临床应用。
制成新型定制化股骨髁人工关节软骨。其与同种异体骨的软骨下骨压配良好。患者随访1年半结果良好。
基于快速成型技术设计制造了新型定制化股骨髁人工关节软骨。结果表明该制造工艺具有快速、精确的优点，这对个体化人工植入物制造非常重要。该人工关节软骨压配良好，可能是解决半关节同种异体移植中异体软骨坏死的一个好方法。
