Westhus Nina
Saint Louis University School of Nursing, Saint Louis, MO, USA.
MCN Am J Matern Child Nurs. 2004 Sep-Oct;29(5):282-7; quiz 290-1. doi: 10.1097/00005721-200409000-00004.
This replication study examined the extent to which feeding-tube aspirates (pH and enzyme content) are effective predictors of feeding tube location in acutely ill children.
A convenience sample of 56 children was obtained at a metropolitan children's hospital. Approximately 2.5 ml of fluid were withdrawn from children's nasogastric, orogastric, or nasointestinal tubes within 30 minutes of radiographic examination. Fluid was tested for pH and enzymes, and results were compared with radiographic results of tube location.
Mean gastric pH was significantly lower than mean intestinal pH. Mean fasting gastric pepsin level was significantly higher than mean fasting intestinal pepsin level. Usual intestinal constituent, trypsin, was significantly higher in the small bowel than in the stomach. Mean fasting trypsin level was 70 microg/ml in the intestine, and only 10 microg/ml in the gastric site. Predictive positive value was >90% for all tests; predictive negative value was < 65%. Colors of the gastric aspirates were distinctly different from those observed in intestinal aspirates.
Methods of aspirating fluid from feeding tubes and testing visually or assaying for aspirate characteristics were found to be adaptable from adults to children. The clinical implications of being able to use a test as simple as pH of feeding aspirates means that nurses can easily test these aspirates in any clinical setting using reliable pH test strips, similar to what was done in this study. These data add evidence that suggests indicators of tube location effective in adults are also effective in children.
本重复研究探讨了饲管抽出物(pH值和酶含量)在多大程度上可有效预测急病患儿饲管的位置。
在一家大城市儿童医院选取了56名儿童作为便利样本。在进行放射检查后30分钟内,从儿童的鼻胃管、口胃管或鼻肠管中抽取约2.5毫升液体。对液体进行pH值和酶检测,并将结果与饲管位置的放射检查结果进行比较。
胃平均pH值显著低于肠平均pH值。空腹胃蛋白酶平均水平显著高于空腹肠蛋白酶平均水平。小肠中常见的肠成分胰蛋白酶显著高于胃中的含量。空腹时胰蛋白酶平均水平在肠道为70微克/毫升,在胃中仅为10微克/毫升。所有检测的预测阳性值均>90%;预测阴性值<65%。胃抽出物的颜色与肠抽出物明显不同。
从饲管抽吸液体并通过肉眼检测或分析抽出物特征的方法已被证明可从成人应用于儿童。能够使用像饲管抽出物pH值这样简单的检测方法的临床意义在于,护士可以在任何临床环境中使用可靠的pH试纸轻松检测这些抽出物,就像本研究中所做的那样。这些数据进一步证明,在成人中有效的饲管位置指标在儿童中也同样有效。