Pialoux G, Fournier S, Dupont B, Fleury J, Sansonetti P, Goldstein F, Trotot P
Hôpital de l'Institut Pasteur, Paris.
Presse Med. 1992 Mar 7;21(9):417-21.
Rhodococcus (Corynebacterium) equi is a well-known Gram positive bacillus which is usually pathogenic in farm animals but rarely causes diseases in humans. Only 30 cases of human infection have been reported in the literature. R. equi has recently been added to the list of opportunistic agents in severe HIV infection. Its most common manifestation in immunocompromised is a slowly progressive pneumonia which may cavitate. R. equi pulmonary infections are difficult to treat: they usually require prolonged parenteral antibiotic therapy and often need surgical treatment. Two cases of cavitary pneumonia in patients with severe HIV infection are reported here. In one case the disease was associated with pulmonary Kaposi sarcoma and pneumocystis pneumonia; the other case was the first opportunistic infection in the course of HIV infection.
马红球菌(马棒状杆菌)是一种著名的革兰氏阳性杆菌,通常对家畜致病,但很少导致人类疾病。文献中仅报道了30例人类感染病例。马红球菌最近已被列入严重HIV感染的机会性病原体名单。其在免疫功能低下者中最常见的表现是可能形成空洞的缓慢进展性肺炎。马红球菌肺部感染难以治疗:通常需要长期的胃肠外抗生素治疗,且常常需要手术治疗。本文报道了2例严重HIV感染患者的空洞性肺炎病例。1例患者的疾病与肺卡波西肉瘤和肺孢子菌肺炎相关;另1例是HIV感染过程中的首例机会性感染。