阻止重塑过程的可行性。

Feasibility of arresting the process of remodeling.

作者信息

Somasundaram P E, Chandrashekhar Y

机构信息

University of Minnesota, Minneapolis, MN 55417, USA.

出版信息

Med Clin North Am. 2004 Sep;88(5):1193-207, x. doi: 10.1016/j.mcna.2004.04.014.

DOI:10.1016/j.mcna.2004.04.014

PMID:15331313

Abstract

Heart failure (HF) is a massive public health issue. Ventricular remodeling is pivotal to the pathophysiology/progression of HF and an attractive target for intervention. It currently is believed that interdicting the natural history of ventricular remodeling will be crucial to controlling the HF epidemic. This article reviews the current data on the feasibility of arresting this process. This review is not meant to be exhaustive but provides a brief overview of the approaches being contemplated in this field.

摘要

心力衰竭（HF）是一个重大的公共卫生问题。心室重构对于HF的病理生理学/进展至关重要，并且是一个有吸引力的干预靶点。目前认为，阻断心室重构的自然病程对于控制HF流行至关重要。本文综述了关于阻止这一过程可行性的当前数据。本综述并非详尽无遗，而是简要概述了该领域正在考虑的方法。