Shen Jun, Chen Zhengguang, Yang Jehoon
Molecular Imaging Branch, National Institute of Mental Health, Bethesda, Maryland, USA.
J Magn Reson Imaging. 2004 Sep;20(3):531-7. doi: 10.1002/jmri.20134.
To propose new frequency offset corrected inversion (FOCI) pulses with significantly reduced radiofrequency (RF) power deposition for spin echo imaging by incorporating the variable-rate selective excitation (VERSE) schemes into the pulse design.
Two schemes are proposed to design the new FOCI pulses with dramatically reduced peak RF power requirements. In scheme A, the time-dilation function is derived from a predefined adiabaticity factor modulation function. In scheme B, the time-dilation function is predefined, while the adiabaticity factor is conserved.
The new FOCI pulses are shown to be able to operate at reduced specific absorption rate (SAR), specifically at the same peak RF power as that of a five- or seven-lobe sinc inversion pulse of the same duration. Using the new FOCI pulse, significant gain in sensitivity was observed in in vivo spin-echo echo-planar imaging, which was attributed to the improved refocusing slice profile.
The new FOCI pulses can replace the 180 degrees five- or seven-lobe sinc pulses in spin-echo imaging with the same peak RF power requirement and significantly improved slice profile.
通过将变速选择性激发(VERSE)方案纳入脉冲设计,提出用于自旋回波成像的具有显著降低射频(RF)功率沉积的新型频率偏移校正反转(FOCI)脉冲。
提出了两种方案来设计具有大幅降低的峰值RF功率要求的新型FOCI脉冲。在方案A中,时间膨胀函数由预定义的绝热因子调制函数导出。在方案B中,时间膨胀函数是预定义的,而绝热因子保持不变。
新型FOCI脉冲显示能够在降低的比吸收率(SAR)下运行,具体而言,在与相同持续时间的五瓣或七瓣 sinc 反转脉冲相同的峰值RF功率下运行。使用新型FOCI脉冲,在体内自旋回波平面成像中观察到灵敏度有显著提高,这归因于改善的重聚焦切片轮廓。
新型FOCI脉冲可以在相同的峰值RF功率要求下取代自旋回波成像中的180度五瓣或七瓣 sinc 脉冲,并显著改善切片轮廓。