III期和IV期胆囊癌手术后的预后因素分析。
Analysis of prognostic factors after surgery for stage III and IV gallbladder cancer.
作者信息
Wakabayashi H, Ishimura K, Hashimoto N, Otani T, Kondo A, Maeta H
机构信息
Department of Surgery, Sakaide Municipal General Hospital, Sakaide-city, Kagawa 762-0031, Japan.
出版信息
Eur J Surg Oncol. 2004 Oct;30(8):842-6. doi: 10.1016/j.ejso.2004.06.001.
AIM
Survival and prognostic factors were analysed in patients who had undergone surgical resection with curative intention with the aim of identifying groups of patient with stage III and IV gallbladder cancer on the TNM classification who might benefit from surgery.
METHODS
Thirty-seven patients with advanced gallbladder cancer were studied, the cumulative survival rate for each group was calculated for each pTNM factor.
RESULTS
The 5-year survival rates in the stage III patients were 83.3%, while those for the stage IVA patients were 46.2%, and those for the stage IVB patients 16.7%.
CONCLUSIONS
In patients with invasion of adjacent organs, including the liver and gastrointestinal tract, and rated as pT3 or pT4, extended surgery excising the invaded tissue may be justified. In patients with pN2 lymph-node metastasis, even without adjacent organ invasion, radical surgery may not achieve a good outcome.
目的
对接受根治性手术切除的患者的生存情况和预后因素进行分析，旨在确定根据TNM分类处于III期和IV期胆囊癌的患者群体，这些患者可能从手术中获益。
方法
研究了37例晚期胆囊癌患者，计算了每个pTNM因素下每组的累积生存率。
结果
III期患者的5年生存率为83.3%，IVA期患者为46.2%，IVB期患者为16.7%。
结论
对于侵犯包括肝脏和胃肠道在内的邻近器官且被评定为pT3或pT4的患者，扩大手术切除受侵组织可能是合理的。对于有pN2淋巴结转移的患者，即使没有邻近器官侵犯，根治性手术也可能无法取得良好效果。
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