Lisowska Anna, Prokop Jolanta, Hirnle Tomasz, Juszczyk Grzegorz, Skibińska Elzbieta, Musiał Włodzimierz J, Klonowska-Dziatkiewicz Ewa
Klinika Kardiologii, Akademia Medyczna, Białystok, Poland.
Kardiol Pol. 2004 Jul;61(7):49-51; discussion 52.
A case of a 27-year-old female with prosthetic mitral valve is presented. Prolonged anticoagulation therapy was continued during pregnancy without complications. During puerperium, the dose of subcutaneous low molecular weight heparin was reduced due to subcutaneous blood effusions. Subsequently, the patient developed acute left ventricular heart failure due to prosthetic valve thrombosis. She underwent urgent surgery with new prosthetic valve implantation. Two weeks later she suffered another episode of acute mitral prosthetic valve thrombosis which was effectively treated with intravenous heparin. Difficulties concerning prolonged anticoagulation during pregnancy and puerperium in patients with prosthetic valves are discussed.
本文介绍了一例27岁的人工二尖瓣置换术后女性病例。患者在孕期持续接受长期抗凝治疗,未出现并发症。产褥期,因皮下出血,皮下低分子肝素剂量减少。随后,患者因人工瓣膜血栓形成发生急性左心室心力衰竭。她接受了紧急手术,植入了新的人工瓣膜。两周后,她再次发生急性人工二尖瓣血栓形成,经静脉注射肝素得到有效治疗。文中讨论了人工瓣膜置换术后患者在孕期和产褥期进行长期抗凝治疗时所面临的困难。