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[十二指肠乳头肿瘤的外科治疗]

[Surgical treatment of major duodenal papilla neoplasm].

作者信息

Skipenko O G, Shatverian G A, Ratnikova N P, Khrustaleva M V, Fisenko E P, Frolov N O, Abdullaev A G

出版信息

Khirurgiia (Mosk). 2004(8):27-31.

PMID:15340314
Abstract

Immediate and long-term results of pancreatoduodenal resections in 33 patients undergone surgery for adenocarcinoma of bile papilla from 1984 to 2003 were studied. Majority of patients had II and III stages of diseases. Correct diagnosis before surgery was made in 27 (81.8%) patients. Morphologic study revealed metastasis in 11 patients. Lethality was 9.1%, moreover last 18 pancreatoduodenal resections had no lethal outcomes. Long-term results were studied in 25 (83.3%) patients: 1-year survival was 90.4%, 3, 5 and 10 years survived 71.4, 61.2 and 51% patients respectively. Only metastatic lesion of lymph nodes and later stage of disease had negative influence on long-term results. Such factors as gender, diameter of carcinoma, lymphadenectomy and pylorus-saving variant of surgery did not influence on long-term results. It is concluded that pancreatoduodenal resection must be surgery of choice in the treatment of resected cancer of bile papilla.

摘要

对1984年至2003年间因胆管乳头腺癌接受手术的33例患者进行胰十二指肠切除术的近期和远期结果进行了研究。大多数患者处于疾病的II期和III期。27例(81.8%)患者在手术前得到了正确诊断。形态学研究显示11例患者有转移。死亡率为9.1%,此外,最近的18例胰十二指肠切除术无死亡病例。对25例(83.3%)患者进行了远期结果研究:1年生存率为90.4%,3年、5年和10年生存率分别为71.4%、61.2%和51%。只有淋巴结转移灶和疾病晚期对远期结果有负面影响。性别、癌肿直径、淋巴结清扫术和保留幽门的手术方式等因素对远期结果无影响。结论是,胰十二指肠切除术必须是治疗可切除胆管乳头癌的首选手术。

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