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An Apollon vista of death and destruction.

作者信息

Martin Seamus J

出版信息

Nat Cell Biol. 2004 Sep;6(9):804-6. doi: 10.1038/ncb0904-804.

DOI:10.1038/ncb0904-804
PMID:15340445
Abstract
摘要

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1
An Apollon vista of death and destruction.一幅死亡与毁灭的可怕景象。
Nat Cell Biol. 2004 Sep;6(9):804-6. doi: 10.1038/ncb0904-804.
2
[Inhibition of apoptosis by a huge UBC protein, Apollon/BRUCE/BIRC6].[一种巨大的泛素结合酶蛋白Apollon/BRUCE/BIRC6对细胞凋亡的抑制作用]
Tanpakushitsu Kakusan Koso. 2006 Aug;51(10 Suppl):1391-4.
3
A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis.一种新型的TUCAN同工型在人类癌组织中过表达,并抑制半胱天冬酶-8和半胱天冬酶-9介导的细胞凋亡。
Cancer Res. 2005 Oct 1;65(19):8706-14. doi: 10.1158/0008-5472.CAN-04-4649.
4
HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells.HtrA2切割Apollon,并通过Apollon缺陷细胞中的IAP结合基序诱导细胞死亡。
Biochem Biophys Res Commun. 2005 Apr 29;330(1):279-85. doi: 10.1016/j.bbrc.2005.02.165.
5
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.IAP拮抗剂可诱导c-IAPs的自身泛素化、NF-κB激活以及TNFα依赖性凋亡。
Cell. 2007 Nov 16;131(4):669-81. doi: 10.1016/j.cell.2007.10.030.
6
Programmed cell death in idiopathic dilated cardiomyopathy is mediated by suppression of the apoptosis inhibitor Apollon.特发性扩张型心肌病中的程序性细胞死亡是由凋亡抑制因子Apollon的抑制作用介导的。
Ann Thorac Surg. 2008 Jul;86(1):109-14; discussion 114. doi: 10.1016/j.athoracsur.2008.03.057.
7
Protease-activated receptors, apoptosis and tumor growth.蛋白酶激活受体、细胞凋亡与肿瘤生长。
Pathophysiol Haemost Thromb. 2008;36(3-4):137-47. doi: 10.1159/000175152. Epub 2009 Jan 27.
8
Cell division: Dodging death at division?细胞分裂:在分裂时躲避死亡?
Nat Rev Mol Cell Biol. 2001 Jan;2(1):8. doi: 10.1038/35048000.
9
Comparative analysis of apoptotic pathways in rat, mouse, and hamster spermatozoa.大鼠、小鼠和仓鼠精子凋亡途径的比较分析。
Mol Reprod Dev. 2006 Oct;73(10):1318-25. doi: 10.1002/mrd.20561.
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The inhibitor of apoptosis proteins as therapeutic targets in cancer.凋亡抑制蛋白作为癌症治疗靶点
Clin Cancer Res. 2007 Oct 15;13(20):5995-6000. doi: 10.1158/1078-0432.CCR-07-0729.

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BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of β-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis.含BIR重复序列的泛素结合酶(BRUCE)在药物性肝纤维化进展和致癌过程中对β-连环蛋白信号通路的调控
World J Hepatol. 2021 Mar 27;13(3):343-361. doi: 10.4254/wjh.v13.i3.343.
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MicroRNA-204 Potentiates the Sensitivity of Acute Myeloid Leukemia Cells to Arsenic Trioxide.miRNA-204 增强急性髓系白血病细胞对三氧化二砷的敏感性。
Oncol Res. 2019 Sep 23;27(9):1035-1042. doi: 10.3727/096504019X15528367532612. Epub 2019 Apr 8.
3
MiR-204 acts as a potential therapeutic target in acute myeloid leukemia by increasing BIRC6-mediated apoptosis.
miR-204 通过增加 BIRC6 介导的细胞凋亡在急性髓系白血病中作为潜在的治疗靶点。
BMB Rep. 2018 Sep;51(9):444-449. doi: 10.5483/bmbrep.2018.51.9.036.
4
Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins.诱导肿瘤细胞死亡:凋亡抑制蛋白的作用
F1000Res. 2017 Apr 27;6:587. doi: 10.12688/f1000research.10625.1. eCollection 2017.
5
Apollon/Bruce is upregulated by Humanin.Apollon/Bruce 被 Humanin 上调。
Mol Cell Biochem. 2014 Dec;397(1-2):147-55. doi: 10.1007/s11010-014-2182-4. Epub 2014 Aug 20.
6
The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis.BIRC6基因作为前列腺癌治疗的新靶点:凋亡抑制剂的双重靶向作用
Oncotarget. 2014 Aug 30;5(16):6896-908. doi: 10.18632/oncotarget.2229.
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BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation.BIRC6(APOLLON)在急性髓系白血病中下调,其敲低可减弱中性粒细胞分化。
Exp Hematol Oncol. 2012 Sep 4;1(1):25. doi: 10.1186/2162-3619-1-25.
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Identification of BIRC6 as a novel intervention target for neuroblastoma therapy.鉴定 BIRC6 为神经母细胞瘤治疗的新干预靶点。
BMC Cancer. 2012 Jul 12;12:285. doi: 10.1186/1471-2407-12-285.
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The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib.新型 Aurora A 激酶抑制剂 MLN8237 对耐药性慢性髓性白血病有效,并显著提高了尼洛替尼的疗效。
J Cell Mol Med. 2011 Oct;15(10):2057-70. doi: 10.1111/j.1582-4934.2010.01218.x.