Denger Karin, Weinitschke Sonja, Hollemeyer Klaus, Cook Alasdair M
Fachbereich Biologie der Universität Konstanz, 78457 Konstanz, Germany.
Arch Microbiol. 2004 Oct;182(2-3):254-8. doi: 10.1007/s00203-004-0678-0. Epub 2004 Aug 31.
Genes thought to encode (a) the regulator of taurine catabolism under carbon-limiting or nitrogen-limiting conditions and (b) taurine dehydrogenase were found in the genome of Rhodopseudomonas palustris. The organism utilized taurine quantitatively as a sole source of nitrogen (but not of carbon) for aerobic and photoheterotrophic growth. No sulfate was released, and the C-sulfonate bond was recovered stoichiometrically as sulfoacetate, which was identified by mass spectrometry. An inducible sulfoacetaldehyde dehydrogenase was detected. R. palustris thus contains a pathway to generate a natural product that was previously believed to be formed solely from sulfoquinovose.
在沼泽红假单胞菌的基因组中发现了被认为编码（a）碳限制或氮限制条件下牛磺酸分解代谢调节因子以及（b）牛磺酸脱氢酶的基因。该微生物能够定量利用牛磺酸作为有氧和光异养生长的唯一氮源（而非碳源）。未释放出硫酸盐，且碳 - 磺酸盐键以硫代乙酸盐的形式按化学计量回收，通过质谱法对其进行了鉴定。检测到一种可诱导的硫代乙醛脱氢酶。因此，沼泽红假单胞菌含有一条生成天然产物的途径，而该天然产物此前被认为仅由磺基奎诺糖形成。
