Bozhinova S, Penkov V, Bogdanova A
Akush Ginekol (Sofiia). 2004;43(3):27-31.
The problem of iron deficiency anaemia (IDA) in pregnant women is not a new one, but the flashback to it is justified because of the fact that its significance is not appreciated properly. The growing foetus has increased needs of different active for blood formation substances such as iron (Fe), folic acid, vit. B12, which are taken away from the mother. If her supplies are not enough, an anaemic syndrome can be promoted. The only suitable way in the presence of iron deficiency is the administration of drugs for equilibration of iron balance. We used Ferro-Folgamma--a new medicine for our pharmaceutical market, for treatment of IDA in 42 pregnant women and we rendered an account of the results of its administration. All pregnant women had starting data of Hb<110 g/l and Hct<0.33 L/L. One capsule of Ferro-Folgamma contains 100 mg iron sulfate siccatum (that corresponds to 37 mg Fe), folic acid - 5 mg, cyancobalamine 10 mg. It is administered a capsule 3 times daily in 1 to 3 courses of treatment and a course has 20 days duration. After a treatment course was carried out the starting data of Hb were increased with 8.73 g/l, and of Hct with 0.02. In 8 pregnant women after the first therapeutic course, a 20-days - treatment was conducted too and Hb rose with 18.14 g/l in comparison with the starting data, and of Hct - with 0.037. The authors recommend the utilization of Ferro-Folgamma for treatment and prophylaxis of IDA in pregnant women, because of its good gastric acceptance, a few side undesired reactions, and the supplement of Folic acid and vit B12 increases the iron resorbtion.
孕妇缺铁性贫血(IDA)问题并非新问题,但回顾这一问题是合理的,因为其重要性未得到充分认识。成长中的胎儿对铁(Fe)、叶酸、维生素B12等不同造血活性物质的需求增加,这些物质会从母亲体内摄取。如果母亲的储备不足,就可能引发贫血综合征。在缺铁的情况下,唯一合适的方法是使用药物来平衡铁平衡。我们使用了Ferro - Folgamma(一种在我们药品市场上的新药)治疗42名孕妇的IDA,并报告了用药结果。所有孕妇的初始数据为血红蛋白(Hb)<110 g/l和血细胞比容(Hct)<0.33 L/L。一粒Ferro - Folgamma胶囊含有100毫克干燥硫酸亚铁(相当于37毫克铁)、5毫克叶酸、10毫克氰钴胺。每日服用3次,每次1粒,进行1至3个疗程的治疗,一个疗程持续20天。一个疗程治疗后,Hb初始数据增加了8.73 g/l,Hct增加了0.02。8名孕妇在第一个治疗疗程后,又进行了20天的治疗,与初始数据相比,Hb升高了18.14 g/l,Hct升高了0.037。作者推荐使用Ferro - Folgamma治疗和预防孕妇IDA,因为它具有良好的胃耐受性、不良反应少,且补充叶酸和维生素B12可增加铁的吸收。