Park Sang-Yoo, Kim Jin Hyung, Kim Ki Taek, Kim Yoo Jung, Kim Tae Hwan, Hwang Keum, Sung Ki Jun, Park Kwang Hwa
Department of Otolaryngology-Head and Neck Surgery, Wonju College of Medicine, Yonsei University, 162 Ilsan-dong, Wonju, Kangwon-do 220-701, Korea.
Yonsei Med J. 2004 Aug 31;45(4):719-22. doi: 10.3349/ymj.2004.45.4.719.
Medulloblastoma is a common malignant central nervous system neoplasm found mainly in children. One the contrary, medulloblastoma of the cerebellopontine angle, the location of the tumor is very unusual. This is the the first case of the medullomyoblastoma, a rare form of medulloblastoma, occurring in the cerebellopontine angle. A 15-year-old boy experienced a sudden hearing loss in the left ear. Conservative medical treatment failed, and temporal MR imaging revealed a heterogeneously enhancing mass at the left cerebellopontine angle cistern and in the internal auditory canal; therefore, the lesion was regarded as a typical acoustic neuroma. Few days before surgery, an ipsilateral facial palsy developed, and a follow-up MR imaging showed a rapid growth of the previous lesion. The extended translabyrinthine approach permitted surgical removal. And under pathological diagnosis of malignancy, radiation therapy and series of chemotherapy was performed.
髓母细胞瘤是一种常见的恶性中枢神经系统肿瘤，主要发生于儿童。相反，位于小脑桥脑角的髓母细胞瘤，其肿瘤位置非常罕见。这是第一例发生在小脑桥脑角的髓肌母细胞瘤，一种罕见的髓母细胞瘤形式。一名15岁男孩左耳突然听力丧失。保守治疗失败，颞部磁共振成像显示左侧小脑桥脑角池和内耳道有不均匀强化肿块；因此，该病变被视为典型的听神经瘤。手术前几天，同侧面部神经麻痹出现，后续磁共振成像显示先前病变迅速生长。扩大经迷路入路允许手术切除。在恶性病理诊断后，进行了放射治疗和一系列化疗。
