Kearvell R, Kuan R, Preston R, Tanner P, Buck H, Hedges R
Department of Radiation Oncology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Perth, Western Australia 6009, Australia.
Australas Radiol. 2004 Sep;48(3):358-63. doi: 10.1111/j.0004-8461.2004.01319.x.
Patients undergoing radiation treatment for head and neck cancer have many critical structures within or adjacent to the treatment area. Avoiding these critical structures is more efficient and easier using 3-D conformal planning. At Sir Charles Gairdner Hospital an investigation into the acute radiation toxicity was undertaken when the head and neck treatment technique was changed from the conventional 2-D plan to the conformal 3-D plan. Although the primary target volume (PTV), fraction size and overall dose remain the same for the two techniques, differing beam configurations mean that treatment fields enter and exit through different parts of the head and neck. Ten patients were initially assessed to gain a baseline appearance of their head and neck region, and then graded weekly according to the toxicity criteria during treatment and at 4, 8 and 12 weeks after treatment. The results of the assessment indicate that there is no increase in toxicity as a result of treating using the conformal head and neck technique.
接受头颈癌放射治疗的患者，其治疗区域内或附近存在许多关键结构。使用三维适形放疗计划来避开这些关键结构更高效、更容易。在查尔斯·盖尔德纳爵士医院，当头颈治疗技术从传统的二维计划改为适形三维计划时，对急性放射毒性进行了一项调查。尽管两种技术的主要靶区体积（PTV）、分次剂量和总剂量保持不变，但不同的射野配置意味着治疗野进出头颈的不同部位。最初对10名患者进行评估，以获取其头颈区域的基线外观，然后在治疗期间以及治疗后4周、8周和12周根据毒性标准每周进行分级。评估结果表明，使用适形头颈技术进行治疗不会导致毒性增加。
