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Laser-assisted end-to-end vascular anastomosis of elastin heterograft to carotid artery with an albumin stent in vivo.

作者信息

Xie Hua, Bendre Suhas C, Gregory Kenton W, Furnary Anthony P

机构信息

Oregon Medical Laser Center, Providence St. Vincent Medical Center, 9555 SW Barnes Road, Portland, OR 97225, USA.

出版信息

Photomed Laser Surg. 2004 Aug;22(4):298-302. doi: 10.1089/pho.2004.22.298.

DOI:10.1089/pho.2004.22.298
PMID:15345171
Abstract

BACKGROUND DATA

Laser-assisted end-to-end vascular anastomosis of an elastin heterograft to native artery may avoid the problems associated with currently available vascular synthetic grafts and conventional suture anastomosis.

METHODS

A total of 21 anastomoses in the carotid arteries of seven domestic pigs were performed with an 800-nm laser and an albumin stent plus solder. There were five artery to artery and 16 elastin heterograft to native artery anastomoses. Operative parameters, vascular patency, and histology of the anastomoses were evaluated.

RESULTS

Out of 21 anastomoses, 20 were patent at 3 h. The average amount of total energy used was 212 Joules in artery to artery anastomosis and 273 Joules in elastin heterograft to native artery. Histology shows coagulative necrosis of the adventitia, hypereosinophilic contraction band in the media in native artery, and no change in elastin heterografts.

CONCLUSIONS

Laser-assisted vascular anastomosis of elastin heterograft to medium size vessel is possible. Albumin stent played an important role in strength of the anastomosis. Chronic studies are warranted to determine long-term patency and histology of the laser-assisted vascular anastomosis.

摘要

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