Sajatovic Martha, Blow Frederic C, Ignacio Rosalinda V, Kales Helen C
Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Psychiatr Serv. 2004 Sep;55(9):1014-21. doi: 10.1176/appi.ps.55.9.1014.
This retrospective analysis of a large Department of Veterans Affairs (VA) database evaluated differences in clinical presentation, health service use, and use of psychotropic medications between older and younger adults with bipolar disorder.
The results presented in this article focus on veterans with bipolar disorder who were active in the VA's National Psychosis Registry in federal fiscal year 2001 (FY01).
The registry listed 65,556 individuals as having bipolar disorder in FY01. In FY01, nearly 25 percent of veterans with bipolar disorder (more than 16,000 individuals) were aged 60 years or older, and more than 10 percent were aged 70 years or older. Elderly persons were hospitalized at similar or slightly lower rates than middle-aged persons but tended to have longer hospital stays. Use of outpatient services was also higher in older populations. Patterns of use of psychotropic medications indicated that valproate is the most commonly used mood-stabilizing agent in the VA, in use by 72.9 percent of patients who receive a mood stabilizer. Use of lithium is substantial as well, with more than 40 percent of patients taking this agent. In addition, just over 40 percent of all veterans with bipolar disorder receive antipsychotic medication.
Bipolar disorder affects large numbers of veterans across the entire life span, and use of VA resources by this population becomes greater with advancing age. Data from this study provide new information about the unique treatment requirements and clinical presentations of older patients with bipolar disorder.
本项对美国退伍军人事务部(VA)大型数据库的回顾性分析评估了双相情感障碍老年和年轻患者在临床表现、医疗服务利用及精神药物使用方面的差异。
本文呈现的结果聚焦于2001财年(FY01)活跃于VA国家精神病登记处的双相情感障碍退伍军人。
该登记处列出2001财年有65556人患有双相情感障碍。在2001财年,近25%的双相情感障碍退伍军人(超过16000人)年龄在60岁及以上,超过10%的人年龄在70岁及以上。老年人住院率与中年人相似或略低,但住院时间往往更长。老年人群门诊服务使用率也更高。精神药物使用模式表明丙戊酸盐是VA最常用的心境稳定剂,72.9%接受心境稳定剂治疗的患者使用该药。锂盐的使用也很普遍,超过40%的患者服用该药。此外,超过40%的双相情感障碍退伍军人接受抗精神病药物治疗。
双相情感障碍影响着各个年龄段的大量退伍军人,且随着年龄增长,该人群对VA资源的利用增加。本研究数据提供了有关双相情感障碍老年患者独特治疗需求和临床表现的新信息。