Singh Meenu
Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Pediatr. 2004 Aug;71(8):721-7. doi: 10.1007/BF02730663.
Several new drugs have resulted from innovative pharmacological and immunomodulatory approaches towards treatment of asthma. Diverse therapeutic targets have provided new agents. The new classes of drugs available are newer "on site activated inhaled corticisteroids" and soft steroids, anti IgE compounds, leukotriene inhibitors and single isomer agents which are available for clinical use. Anti interleukin agents and phosphodiesterase inhibitors are in the stage of clinical trials. Antisense therapy and pharmacogenetics are the on horizon for treatment of asthma.
几种新药源于治疗哮喘的创新药理学和免疫调节方法。多样的治疗靶点带来了新的药物。现有的新型药物包括更新的“局部激活吸入性皮质类固醇”和软类固醇、抗IgE化合物、白三烯抑制剂以及可供临床使用的单一异构体药物。抗白细胞介素药物和磷酸二酯酶抑制剂正处于临床试验阶段。反义疗法和药物遗传学在哮喘治疗方面即将出现。