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[葡萄糖跨小肠黏膜的转运]

[Glucose transport across the mucosa of the small intestine].

作者信息

Kosarev A V

出版信息

Vopr Pitan. 1976 Jul-Aug(4):29-9.

PMID:15346
Abstract

The rate of glucose absorption in an isolated loop of the small intestine in rats was measured. The maximum rate of absorption was registered with 3 and 5 per cent concentrations, while 1 and 10 per cent solutions are absorbed at a slower rate. The absorption rate of 5 per cent glucose solution did not materially change for one hour after a sugar load. The small intestine mucosa transports glucose from a 5 per cent solution at an equal rate in rats and rabbits, i. e. 139+/-4 and 143+/-6 gamma/cm2/min. Maximum absorption takes place with pH of 6-8. Deviation of the pH value to acidity and alkalinity is attended by steep fall in the absorption rate. At pH of 3.0 and 11.5 the absorption virtually ceases altogether. Hexobarbital anesthesia depresses absorption of glucose in the intestine by a factor of 2-3.5.

摘要

测定了大鼠离体小肠肠袢中葡萄糖的吸收速率。最大吸收速率出现在3%和5%的浓度时,而1%和10%的溶液吸收速率较慢。糖负荷后一小时,5%葡萄糖溶液的吸收速率没有实质性变化。大鼠和兔子的小肠黏膜以相同速率转运5%溶液中的葡萄糖,即139±4和143±6微克/平方厘米/分钟。pH值为6 - 8时吸收量最大。pH值向酸性和碱性偏离时,吸收速率会急剧下降。在pH值为3.0和11.5时,吸收几乎完全停止。己巴比妥麻醉使肠道中葡萄糖的吸收降低2 - 3.5倍。

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