Samra H K, Ganguly N K, Garg U C, Goyal J, Mahajan R C
Department of Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Biochem Int. 1988 Nov;17(5):801-12.
The transport of D-glucose and L-phenylalanine was measured in intestinal brush border membrane (BBM) vesicles treated with Excretory-secretory (ES) products of Giardia lamblia. Uptake was found to be significantly lower (P/0.01) in the treated vesicles than in the controls. Exposure of intestinal tissue to ES products resulted in net secretion (P/0.01) of Na+, C1- and 3-O-methyl-D-glucose. Both observations indicate that alterations in the absorptive functions of the intestine might be attributed to interaction of ES products with the BBM.
在经蓝氏贾第鞭毛虫排泄-分泌（ES）产物处理的肠刷状缘膜（BBM）囊泡中测定了D-葡萄糖和L-苯丙氨酸的转运。结果发现，处理后的囊泡摄取量显著低于对照组（P<0.01）。将肠组织暴露于ES产物导致Na⁺、Cl⁻和3-O-甲基-D-葡萄糖的净分泌（P<0.01）。这两项观察结果均表明，肠道吸收功能的改变可能归因于ES产物与BBM的相互作用。
