肝移植术后丙型肝炎感染的自然史及管理

Natural history and management of hepatitis C infection after liver transplantation.

作者信息

Charlton Michael, Wiesner Russell

机构信息

Department of Gastroenterology and Hepatology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.

出版信息

Semin Liver Dis. 2004;24 Suppl 2:79-88. doi: 10.1055/s-2004-832932.

DOI:10.1055/s-2004-832932

PMID:15346250

Abstract

With almost universal virological recurrence and a projected several-fold increase in HCV-related end-stage liver disease within the next decade, a clear understanding of the natural history of posttransplant HCV infection and optimization of the management of recurrent HCV infection are imperative. This article describes the natural history, risk factors, and current strategies for the amelioration of posttransplant HCV infection.

摘要

由于几乎普遍存在病毒学复发情况，且预计在未来十年内丙型肝炎病毒（HCV）相关终末期肝病将增加数倍，因此必须清楚了解移植后HCV感染的自然史，并优化复发性HCV感染的管理。本文描述了移植后HCV感染的自然史、危险因素以及当前改善该感染的策略。