Herzog Andrew G, Harden Cynthia L, Liporace Joyce, Pennell Page, Schomer Donald L, Sperling Michael, Fowler Kristen, Nikolov Blagovast, Shuman Sevie, Newman Melanee
Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215.
Ann Neurol. 2004 Sep;56(3):431-4. doi: 10.1002/ana.20214.
This investigation assessed the frequency of catamenial epilepsy in 87 women who charted seizures and menses during three cycles. Catamenial epilepsy designation was made if two of three cycles showed at least one of three previously defined catamenial patterns. Among ovulatory cycles, average daily seizure frequency was significantly greater during the perimenstrual and preovulatory phases. Among anovulatory cycles, average daily seizure frequency was substantially less during the midfollicular phase than during the remainder of the cycle. Overall, 39.1% of the women had catamenial epilepsy.
这项调查评估了87名在三个月经周期记录癫痫发作和月经情况的女性中月经性癫痫的发生率。如果三个周期中的两个周期出现了之前定义的三种月经模式中的至少一种,则诊断为月经性癫痫。在有排卵的周期中,月经前期和排卵前期的平均每日癫痫发作频率显著更高。在无排卵的周期中,卵泡中期的平均每日癫痫发作频率比周期的其余时间显著更低。总体而言,39.1%的女性患有月经性癫痫。