Hwang Shin, Lee Sung-Gyu, Lee Young-Joo, Park Kwang-Min, Kim Ki-Hun, Ahn Chul-Soo, Sung Kyu-Bo, Moon Deok-Bog, Ha Tae-Yong, Kim Keon-Kuk, Kim Yeon-Dae
Department of Surgery, Division of Hepatopancreatobiliary Surgery and Liver Transplantation, Ulsan University College of Medicine, Seoul, Korea.
Liver Transpl. 2004 Sep;10(9):1150-5. doi: 10.1002/lt.20225.
The right posterior segment (RPS) graft was introduced to overcome graft-size mismatch when the donor liver demonstrates a disproportionately small left lobe (LL). As variants of liver anatomy seemed to be related to the feasibility of RPS graft procurement, in 2003, we performed a prospective study to assess its feasibility in 197 consecutive living donors. Variants of the portal vein (PV) were classified as type I (bifurcation), II (trifurcation), and III (independent RPS PV branching from main PV). The right hepatic artery, vein, and bile duct were also classified according to their branching pattern and location. PV variations were type I in 157 (79.7%) donors, type II in 15 (7.6%) donors, and type III in 25 (12.7%) donors. Mean volume proportion of LL plus caudate lobe was 35.3 +/- 3.8% (range 24-4) of the whole liver volume (WLV). On exclusion of donors with LL greater than 35% of WLV, there were 14 (7.1%) donors revealing RPS greater than LL by over 3% of WLV. Of these 14 donors, 3 had type I PV with artery or bile duct anatomy not suitable for RPS procurement. One donor with type II PV and 9 out of 10 donors with type III PV met the anatomical conditions for RPS graft procurement. With the exclusion of caudate lobe volume, LL volume became less than 30% of WLV in all of these 14 donors. We successfully procured 3 RPS grafts, all with type III PV, out of 197 consecutive living donors. In conclusion, successful RPS graft procurement is highly possible, only when LL is disproportionately small (<30% of WLV) and the PV variant is type III.
当供体肝脏左叶明显过小时,采用右后段(RPS)移植物来克服移植物大小不匹配的问题。由于肝脏解剖变异似乎与RPS移植物获取的可行性相关,2003年,我们进行了一项前瞻性研究,评估197例连续活体供体中RPS移植物获取的可行性。门静脉(PV)变异分为I型(分叉)、II型(三分叉)和III型(RPS门静脉从主门静脉独立分支)。肝右动脉、静脉和胆管也根据其分支模式和位置进行分类。157例(79.7%)供体的PV变异为I型,15例(7.6%)供体为II型,25例(12.7%)供体为III型。左叶加尾状叶的平均体积比例为全肝体积(WLV)的35.3±3.8%(范围24 - 4)。排除左叶大于WLV 35%的供体后,有14例(7.1%)供体的RPS比左叶大超过WLV的3%。在这14例供体中,3例I型PV的供体其动脉或胆管解剖结构不适合获取RPS移植物。1例II型PV供体和10例III型PV供体中的9例符合RPS移植物获取的解剖条件。排除尾状叶体积后,这14例供体的左叶体积均小于WLV的30%。在197例连续活体供体中,我们成功获取了3例RPS移植物,均为III型PV。总之,只有当左叶明显过小(<WLV的30%)且PV变异为III型时,才极有可能成功获取RPS移植物。