用于硼中子俘获治疗中超热中子束表征的工具包。

A toolkit for epithermal neutron beam characterisation in BNCT.

作者信息

Auterinen Iiro, Serén Tom, Uusi-Simola Jouni, Kosunen Antti, Savolainen Sauli

机构信息

VTT Processes, VTT Technical Research Centre of Finland, P.O. Box 1608, FIN-02044 VTT, Finland.

出版信息

Radiat Prot Dosimetry. 2004;110(1-4):587-93. doi: 10.1093/rpd/nch151.

DOI:10.1093/rpd/nch151

PMID:15353713

Abstract

Methods for dosimetry of epithermal neutron beams used in boron neutron capture therapy (BNCT) have been developed and utilised within the Finnish BNCT project as well as within a European project for a code of practise for the dosimetry of BNCT. One outcome has been a travelling toolkit for BNCT dosimetry. It consists of activation detectors and ionisation chambers. The free-beam neutron spectrum is measured with a set of activation foils of different isotopes irradiated both in a Cd-capsule and without it. Neutron flux (thermal and epithermal) distribution in phantoms is measured using activation of Mn and Au foils, and Cu wire. Ionisation chamber (IC) measurements are performed both in-free-beam and in-phantom for determination of the neutron and gamma dose components. This toolkit has also been used at other BNCT facilities in Europe, the USA, Argentina and Japan.

摘要

用于硼中子俘获疗法（BNCT）的超热中子束剂量测定方法已在芬兰BNCT项目以及一个关于BNCT剂量测定实践规范的欧洲项目中得到开发和应用。一个成果是一个用于BNCT剂量测定的便携式工具包。它由活化探测器和电离室组成。自由束中子能谱通过一组不同同位素的活化箔片来测量，这些箔片在有镉胶囊和无镉胶囊的情况下均进行辐照。使用锰箔、金箔和铜丝的活化来测量模体中的中子通量（热中子和超热中子）分布。在自由束和模体中均进行电离室（IC）测量，以确定中子和伽马剂量分量。这个工具包也已在欧洲、美国、阿根廷和日本的其他BNCT设施中使用。