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线性能量传递的被动光谱法:发展与应用。

Passive spectrometry of linear energy transfer: development and use.

作者信息

Spurný F, Molokanov A G, Bamblevski V P

机构信息

Nuclear Physics Institute, Dept. of Radiation Dosimetry, Czech Academy of Sciences, Na Truhlárce 39/64, 18086 Praha 8, Czech Republic. spurnyqujf.cas.cz

出版信息

Radiat Prot Dosimetry. 2004;110(1-4):675-9. doi: 10.1093/rpd/nch148.

Abstract

A linear energy transfer (LET) spectrometer based on the evaluation of particle track parameters in a chemically etched polyallyldiglycolcarbonate (PADC) track detector has been developed at our laboratory. It permits us to determine LET spectra between 10 and 700 keV microm(-1) in tissues. The LET spectra obtained permit us to calculate total dose and dose equivalent corresponding to particles with etchable tracks also. We have recently been able to verify the calibration curves used by using C, Mg, Ne, Si and Fe ion beams with different energies. The calibration curves obtained are presented and compared with those originally used, and a good correlation is found. The LET spectrometer with new calibration was used to analyse the radiation quality of the radiotherapy proton beam at the Joint Institute for Nuclear Research (JINR). The radiation quality was studied along the proton's range, particular attention being devoted to the region of the Bragg peak. It was found that the biologically weighted effective dose (BWE) reaches a value of about 1.25 at the Bragg peak region. At the beam entrance this value increases to about 1.02 due to secondary particles created through primary proton nuclear reactions in tissues.

摘要

我们实验室已研制出一种基于评估化学蚀刻聚二烯丙基二甘醇碳酸酯(PADC)径迹探测器中粒子径迹参数的线性能量传递(LET)谱仪。它使我们能够确定组织中10至700 keV·μm⁻¹之间的LET谱。所获得的LET谱还使我们能够计算与具有可蚀刻径迹的粒子相对应的总剂量和剂量当量。最近,我们通过使用不同能量的碳、镁、氖、硅和铁离子束验证了所使用的校准曲线。给出了获得的校准曲线并与最初使用的曲线进行比较,发现有良好的相关性。采用新校准的LET谱仪对联合核研究所(JINR)的放射治疗质子束的辐射质量进行了分析。沿着质子射程研究了辐射质量,特别关注布拉格峰区域。发现在布拉格峰区域生物加权有效剂量(BWE)达到约1.25的值。在束流入口处,由于组织中初级质子核反应产生的次级粒子,该值增加到约1.02。

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