Wanhainen Anders, Rosén Carina, Rutegård Jörgen, Bergqvist David, Björck Martin
Department of Surgery, Uppsala University Hospital, Uppsala, Sweden.
Ann Vasc Surg. 2004 May;18(3):287-93. doi: 10.1007/s10016-004-0021-x.
The objective of this study was to evaluate the effect on quality of life (QOL) of screening for abdominal aortic aneurysm (AAA) in a population-based AAA screening program. Twenty-four patients with screening-detected AAA and 45 controls with normal aortic diameter were studied in a prospective, controlled, population-based study. Prior to and 12 months after the ultrasonography examination, all participants completed Short-Form 36 and at 12 months, 10 AAA-specific questions were added. Comparisons were made between the two groups (AAA patients and controls), within each group, and between the groups and norms for the general Swedish population in the same age interval. Our results showed that screening for AAA results in impairment of QOL among those who have the disease and who suffered a low QOL prior to screening. Among those who had an age-adjusted normal QOL prior to screening and who were found to have the disease, and among those who were found to have normal aortas, no negative effect on QOL was observed. Thus, low QOL before screening is a possible risk factor for negative mental effects of diagnosing an AAA by screening.
本研究的目的是评估在基于人群的腹主动脉瘤(AAA)筛查项目中,对腹主动脉瘤进行筛查对生活质量(QOL)的影响。在一项前瞻性、对照、基于人群的研究中,对24例经筛查发现腹主动脉瘤的患者和45例主动脉直径正常的对照者进行了研究。在超声检查前和检查后12个月,所有参与者均完成了36项简明健康状况调查量表,在12个月时,增加了10个特定于腹主动脉瘤的问题。对两组(腹主动脉瘤患者和对照者)之间、每组内部以及两组与同一年龄段瑞典普通人群的标准之间进行了比较。我们的结果表明,对腹主动脉瘤进行筛查会导致患病且在筛查前生活质量较低的人群的生活质量受损。在筛查前年龄调整后的生活质量正常且被发现患有该病的人群中,以及在被发现主动脉正常的人群中,未观察到对生活质量有负面影响。因此,筛查前生活质量较低是通过筛查诊断腹主动脉瘤产生负面心理影响的一个可能风险因素。