Department of Cardiovascular Sciences and National Institute for Health Research Leicester Biomedical Research Unit, University of Leicester, Leicester Royal Infirmary, Leicester, UK.
Br J Surg. 2018 Feb;105(3):203-208. doi: 10.1002/bjs.10721.
Screening for abdominal aortic aneurysm (AAA) is known to reduce AAA-related mortality; however, the psychological impact of population AAA screening is unclear. The aim was to assess the impact of AAA diagnosis on quality of life (QoL) using data from an established AAA screening programme.
Mental and physical QoL scores for men diagnosed with AAA through participation in the English and Welsh AAA screening programmes were compared with no-AAA controls. Participants were identified through the United Kingdom Aneurysm Growth Study (UKAGS), a nationwide prospective cohort study of men with an AAA of less than 55 mm diagnosed through voluntary participation in screening. The UKAGS participants completed QoL questionnaires at the time of screening and annually thereafter.
A transient reduction in mental QoL scores was observed following the diagnosis of AAA, returning to baseline levels after 12 months. Physical QoL remained consistently lower in the AAA cohort. Participants thought about their AAA and the AAA growth progressively less 12 months after the initial screening diagnosis. AAA growth rate had no influence over QoL parameters.
This study suggests that screening for AAA does reduce mental QoL; however, this effect is transient (less than 12 months). Men diagnosed with AAA have a consistently worse physical QoL compared with controls.
腹部主动脉瘤(AAA)筛查已被证实可降低与 AAA 相关的死亡率;然而,人群 AAA 筛查的心理影响尚不清楚。本研究旨在利用既定的 AAA 筛查计划的数据来评估 AAA 诊断对生活质量(QoL)的影响。
通过参与英格兰和威尔士 AAA 筛查计划诊断为 AAA 的男性的心理和生理 QoL 评分与无 AAA 对照组进行比较。通过英国动脉瘤生长研究(UKAGS)识别参与者,这是一项针对小于 55mm 的 AAA 男性的全国性前瞻性队列研究,通过自愿参与筛查进行诊断。UKAGS 参与者在筛查时和此后每年完成 QoL 问卷。
在诊断出 AAA 后,心理 QoL 评分短暂下降,12 个月后恢复到基线水平。AAA 队列的生理 QoL 始终较低。在初次筛查诊断后 12 个月,参与者对 AAA 和 AAA 生长的思考逐渐减少。AAA 生长速度对 QoL 参数没有影响。
本研究表明,AAA 筛查确实会降低心理 QoL;然而,这种影响是短暂的(不到 12 个月)。与对照组相比,被诊断为 AAA 的男性的生理 QoL 始终较差。