Wang Shao-Chuan, Hsu Yen-Shen, Chen Kuang-Kuo, Chang Luke S
Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2004 May;67(5):235-8.
Crystallographic composition of urinary tract stone varies in several chemical groups and determines the degree of fragmentation to extracorporeal shock wave lithotripsy (ESWL) which has been widely used for the treatment of renal and ureteral calculi. Visual prediction of stone composition by its morphology from plain radiograph may provide a simple method and clinical hint to decide therapeutic modalities. A prospective study was designed to determine the correlation of stone composition with its radiographic morphology.
One hundred patients of urolithiasis with passage of stone fragments (after ESWL, surgical lithotomy or endoscopic lithotripsy) analyzed as pure stone by infrared spectrometry were reviewed by plain abdominal film to classify their morphology, location and size. Five experienced surgeons familiar with the radiographic patterns of different types of pure stones were invited to predict the stone composition on plain abdominal film.
Five different patterns of radiographic appearances of the stones were identified. Calcium oxalate monohydrate referred to the smooth-shaped and homogeneous ones with denser opacity. Calcium oxalate dihydrate referred to those smaller ones that had irregular margin with stippled border and were less dense. Calcium phosphate (CaP) had moderate density and size without significant figures. Struvite meant staghorn stone; usually bilateral. Uric acid referred to those being radiolucent, slightly opacified, and in large size. The 5 surgeons achieved an overall accuracy of 27.4%. There was no obvious relations between accuracy and location or size of the stones. CaP stone was the most likely to be misclassified, and achieved only 20% accuracy.
Different stone composition showed grossly specific radiographic appearances, but clinical test revealed poor correct rate in prediction of stone composition from plain abdominal film. The results of our study suggest that prediction of stone component based on stone morphology on plain abdominal film may not be accurate enough. Patient's clinical information and other laboratory data should be considered while interpreting plain abdominal film for better treatment choice of urolithiasis.
尿路结石的晶体组成在几个化学组中有所不同,并决定了体外冲击波碎石术(ESWL)的碎石程度,该技术已广泛用于治疗肾和输尿管结石。通过腹部平片上结石的形态对结石成分进行视觉预测,可能为决定治疗方式提供一种简单的方法和临床提示。一项前瞻性研究旨在确定结石成分与其放射学形态之间的相关性。
对100例尿路结石患者进行回顾性分析,这些患者的结石碎片(经ESWL、手术取石或内镜碎石后)经红外光谱分析为纯结石,通过腹部平片对其形态、位置和大小进行分类。邀请5位熟悉不同类型纯结石放射学表现的经验丰富的外科医生,根据腹部平片预测结石成分。
确定了结石的5种不同放射学表现模式。一水草酸钙表现为形状光滑、均匀且密度较高的不透明结石。二水草酸钙表现为那些较小的、边缘不规则且边界有斑点、密度较低的结石。磷酸钙(CaP)密度和大小适中,无明显特征。鸟粪石指鹿角形结石,通常为双侧。尿酸结石表现为透光、轻度不透明且体积较大。这5位外科医生的总体准确率为27.4%。准确率与结石的位置或大小之间无明显关系。CaP结石最容易被误诊,准确率仅为20%。
不同的结石成分显示出大致特定的放射学表现,但临床测试表明,根据腹部平片预测结石成分的正确率较低。我们的研究结果表明,基于腹部平片上结石形态预测结石成分可能不够准确。在解读腹部平片以更好地选择尿路结石治疗方案时,应考虑患者的临床信息和其他实验室数据。