Tobelem G, Economou C, Thomas J, Arvis G
Service d'Urologie, Hôpital Saint-Antoine, Paris.
Ann Urol (Paris). 1987;21(5):362-7.
The systematic collection and filtration of urine for three days after extracorporeal shock wave lithotripsy (ECSWL) has enabled the chemical analysis of the stones treated in 90% of cases. We have been able to demonstrate a correlation between the chemical nature and the mode of fragmentation of the stones. Calcium oxalate monohydrate, brushite and cystine stones form fairly large, well separated, angular fragments with sharp edges. Calcium oxalate dihydrate, calcium phosphate and magnesium ammonium-phosphate (struvite) stones are reduced to an amorphous dust. These findings have direct therapeutic implications, as it is absolutely essential to make sure that no large stone fragments are left in the urinary tract after lithotripsy. These elements led us to try to evaluate the chemical nature and the hardness of the stones on the basis of the radiological findings, in order to adopt the best possible therapeutic strategy. Calcium oxalate dihydrate stones have a striated, spiky and non-homogeneous appearance on plain X-rays. They are frequently responsible for filling defects on intravenous pyelography. They are friable stones which are easily fragmented. In contrast, calcium oxalate monohydrate stones present a regular homogeneous opacity on plain X-rays with no filling defect on intravenous pyelography. These stones are hard and are broken up, with difficulty, into large fragments on the initial fluoroscopic images at the start of treatment. Many stones have a mixed composition (calcium oxalate monohydrate, calcium oxalate dihydrate and calcium phosphates): the plain X-ray does not provide sufficient information and the presence of a filling defect on intravenous pyelography may or may not be suggestive of a friable stone.(ABSTRACT TRUNCATED AT 250 WORDS)
体外冲击波碎石术(ECSWL)后连续三天对尿液进行系统收集和过滤,使得90%的病例中所治疗结石能够进行化学分析。我们已经能够证明结石的化学性质与碎裂方式之间存在关联。一水合草酸钙、透钙磷石和胱氨酸结石会形成相当大、分离良好且有棱角、边缘锋利的碎片。二水合草酸钙、磷酸钙和磷酸镁铵(鸟粪石)结石则会碎成无定形粉末。这些发现具有直接的治疗意义,因为确保碎石术后尿路中不残留大的结石碎片至关重要。这些因素促使我们试图根据放射学检查结果评估结石的化学性质和硬度,以便采取最佳治疗策略。二水合草酸钙结石在普通X射线上呈现出条纹状、尖刺状且不均匀的外观。它们常常导致静脉肾盂造影出现充盈缺损。它们是易碎结石,很容易碎裂。相比之下,一水合草酸钙结石在普通X射线上呈现规则的均匀不透光区,静脉肾盂造影无充盈缺损。这些结石坚硬,在治疗开始时的初始荧光透视图像上很难碎成大的碎片。许多结石具有混合成分(一水合草酸钙、二水合草酸钙和磷酸钙):普通X射线提供的信息不足,静脉肾盂造影上充盈缺损的存在可能提示也可能不提示结石易碎。(摘要截选至250词)