从拟南芥到农业：提高大豆中维生素E含量的工程研究
From Arabidopsis to agriculture: engineering improved Vitamin E content in soybean.
作者信息
Sattler Scott E, Cheng Zigang, DellaPenna Dean
机构信息
Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824-1319, USA.
出版信息
Trends Plant Sci. 2004 Aug;9(8):365-7. doi: 10.1016/j.tplants.2004.06.002.
For more than 80 years, tocopherols have been known to be an essential nutrient, vitamin E, for humans and animals. Work in recent years has concentrated on dissecting tocopherol biosynthesis to engineer the pathway in agricultural crops. Molecular dissection of the pathway in plants is now complete with the cloning and characterization of the gene for Arabidopsis MPBQ/MSBQ methyltransferase (VITAMIN E 3; VTE3). Alison Van Eennemaan and colleagues used seed-specific expression of two vitamin E pathway methyltransferases to engineer increased vitamin E activity in soybeans.
80多年来，生育酚一直被认为是人和动物必需的营养素——维生素E。近年来的研究工作主要集中在剖析生育酚的生物合成过程，以便在农作物中对该途径进行工程改造。随着拟南芥MPBQ/MSBQ甲基转移酶（维生素E 3；VTE3）基因的克隆和特性分析，植物中该途径的分子剖析现已完成。艾莉森·范·埃内曼及其同事利用两种维生素E途径甲基转移酶的种子特异性表达，在大豆中提高了维生素E的活性。
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