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[正常状态及急性乙醇中毒时人脑某些结构的形态测量特征]

[Morphometric characteristic of some structures of the human brain in normal conditions and in acute ethanol intoxication].

作者信息

Shormanov S V, Shormanova N S

出版信息

Morfologiia. 2004;125(3):56-60.

Abstract

In order to establish the neuro-stromal interrelations in the human brain under normal conditions and after extreme influences, different parts of this organ were studied in 14 persons who died suddenly and in 20 persons who died of ethyl alcohol poisoning. A complex of histological, histochemical, planimetric and morphometric methods were used. The specific area of normal neurocytes was shown to be the largest in the medulla oblongata, while that one of the fibers--in the cerebral cortex. Vascularization of the latter is minimal, being much higher in the medulla oblongata. In alcohol intoxication, the area, occupied by neurocytes, was decreased in the cerebral cortex, thalamus and cerebellum due to the destruction of some portion of these cells. In the medulla oblongata neurocytes appear to be more resistant to ethanol. The capillary diameter in the brain areas studied decreased because of the drop in the tone of cerebral arteries, but the number of these vessels per standard area of section was increased as a result of compensatory opening of reserve capillaries.

摘要

为了确定正常情况下以及在极端影响后人类大脑中神经-基质的相互关系,对14例猝死人员和20例死于乙醇中毒人员的该器官不同部位进行了研究。采用了组织学、组织化学、平面测量和形态测量等综合方法。结果显示,正常神经细胞的特定面积在延髓中最大,而纤维的特定面积在大脑皮层中最大。大脑皮层的血管化程度最低,延髓中的血管化程度则高得多。在酒精中毒时,由于大脑皮层、丘脑和小脑中部分神经细胞被破坏,这些区域中神经细胞所占面积减小。在延髓中,神经细胞似乎对乙醇更具抵抗力。由于脑动脉张力下降,所研究脑区的毛细血管直径减小,但由于储备毛细血管的代偿性开放,每单位标准切片面积内的血管数量增加。

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