Modlin Irvin M, Kidd Mark, Lye Kevin D
Gastrointestinal Surgical Pathobiology Research Group, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Eur J Surg. 2002;168(12):669-83. doi: 10.1080/11024150201680022.
In recent times gastric carcinoid tumours have become the subject of substantial clinical interest as knowledge of their biological background and clinical importance has increased Gastric carcinoid tumours have long been considered rare lesions, amounting to less than 2% of all carcinoid tumours and less than 1% of all stomach neoplasms. New large databases suggest that the prevalence of gastric carcinoid is rising, with a true value now closer to 5% of all carcinoids. A tripartite classification system for gastric carcinoid tumours is now in common use: tumours associated with chronic atrophic gastritis; tumours associated with Zollinger-Ellison syndrome; and sporadic lesions. Gastric carcinoids associated with hypergastrinaemia are relatively benign, while sporadic lesions require aggressive surgical management. Gastric carcinoids, however, can be managed initially by endoscopic excision of accessible tumours, followed by regular endoscopic surveillance.
近年来，随着对胃类癌肿瘤生物学背景和临床重要性的认识不断增加，它们已成为大量临床关注的对象。长期以来，胃类癌肿瘤一直被认为是罕见病变，在所有类癌肿瘤中占比不到2%，在所有胃肿瘤中占比不到1%。新的大型数据库表明，胃类癌的患病率正在上升，目前的真实比例更接近所有类癌的5%。目前常用的胃类癌肿瘤三方分类系统如下：与慢性萎缩性胃炎相关的肿瘤；与卓-艾综合征相关的肿瘤；以及散发性病变。与高胃泌素血症相关的胃类癌相对良性，而散发性病变则需要积极的手术治疗。然而，胃类癌最初可以通过内镜切除可触及的肿瘤，然后进行定期内镜监测来处理。
