Nimri Laila F, Elnasser Ziad, Batchoun Raymond
Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan.
FEMS Immunol Med Microbiol. 2004 Oct 1;42(2):255-9. doi: 10.1016/j.femsim.2004.05.014.
Polymicrobial infections associated with diarrhoea are common in developing countries. Stool specimens were collected from 220 patient children and 100 controls. Potential pathogenic agents isolated from 143 (65%) children were identified by molecular and standard microbiological methods. Co-infections with two or more agents were detected in 50 (35%) cases. Escherichia coli, Shigella dysenteriae, Giardia and Entamoeba histolytica were found to be predominant. The etiologic agents could not be determined in 77 (35%) cases. The most significant risk factors were the age, the education level of the mother and the use of non-chlorinated water. The high infection rate of diarrhoeal diseases is a strong indication that these pathogens circulate easily through the population.
在发展中国家,与腹泻相关的混合感染很常见。从220名患病儿童和100名对照者中采集了粪便样本。通过分子生物学和标准微生物学方法,从143名(65%)儿童中分离出潜在病原体。在50例(35%)病例中检测到两种或更多病原体的合并感染。发现大肠杆菌、痢疾志贺菌、贾第虫和溶组织内阿米巴是主要病原体。在77例(35%)病例中无法确定病原体。最显著的风险因素是年龄、母亲的教育水平和使用未氯化水。腹泻疾病的高感染率有力表明这些病原体很容易在人群中传播。