小儿肾移植中的当前免疫抑制剂：疗效、副作用及应用

Current immunosuppressive agents in pediatric renal transplantation: efficacy, side-effects and utilization.

作者信息

Smith Jodi M, Nemeth Thomas L, McDonald Ruth A

机构信息

Division of Nephrology, Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way, Seattle, WA 98105, USA.

出版信息

Pediatr Transplant. 2004 Oct;8(5):445-53. doi: 10.1111/j.1399-3046.2004.00209.x.

DOI:10.1111/j.1399-3046.2004.00209.x

PMID:15367279

Abstract

Advances in immunosuppressive therapy over the past decade have led to dramatic improvements in graft survival. The immunosuppression that is used is center-dependent and is constantly evolving with the development of new medications. The goal remains to find the best combination that will optimize graft survival, while minimizing the adverse effects.

摘要

过去十年间免疫抑制疗法的进展显著提高了移植物的存活率。所采用的免疫抑制方法因中心而异，且随着新药物的研发不断演变。目标仍是找到最佳组合，在将副作用降至最低的同时，优化移植物的存活率。